Therapeutic antibodies with reduced side effect
First Claim
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1. A pharmaceutical comprising:
- (a) a therapeutic protein that binds to a therapeutic target, said protein being modified with a compound that inhibits binding of the protein to the therapeutic target, said modified protein being effective for reducing side effects caused by the protein and for producing a therapeutic effect by binding to the therapeutic target; and
(b) a pharmaceutical carrier.
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Abstract
A therapeutic protein, such as a therapeutic antibody, that is modified with a compound that inhibits binding of the protein to its therapeutic target, thereby reducing side effects caused by the protein.
36 Citations
16 Claims
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1. A pharmaceutical comprising:
(a) a therapeutic protein that binds to a therapeutic target, said protein being modified with a compound that inhibits binding of the protein to the therapeutic target, said modified protein being effective for reducing side effects caused by the protein and for producing a therapeutic effect by binding to the therapeutic target; and
(b) a pharmaceutical carrier.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
Specification