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Hedgehog antagonists, methods and uses related thereto

  • US 20040110663A1
  • Filed: 08/29/2003
  • Published: 06/10/2004
  • Est. Priority Date: 10/13/2000
  • Status: Active Grant
First Claim
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1. A method of inhibiting at least one of unwanted growth, proliferation or survival of a cell, comprising (a) determining whether said cell expresses a gli gene, and (b) contacting said cell which expresses a gli gene with an effective amount of a hedgehog antagonist;

  • wherein contacting said cell with said hedgehog antagonist decreases at least one of cell growth, proliferation or survival.

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