Respiration signal measurement apparatus, systems, and methods

• US 20040116820A1
• Filed: 12/13/2002
• Published: 06/17/2004
• Est. Priority Date: 12/13/2002
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Scheiner, Avram, Zhu, Qingsheng, Daum, Douglas R.
• Granted Patent: US 7,101,339 B2
• Time in Patent Office: Days
• US Class Current: 600/547
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance

Abstract

A cardiac rhythm management apparatus and system may include a first sensor to sense an atrial respiration signal, a second sensor to sense a ventricular respiration signal, and a measurement module capable of being communicatively coupled to the first and second sensors to monitor the atrial and ventricular respiration signals and to select a resulting signal as an indication of respiration. An article may cause a machine to implement a method which includes measuring a second signal responsive to a first signal, measuring a third signal responsive to a first signal, determining a respiration-to-cardiac ratio associated with each one of the second and third signals, and providing a resulting signal including a selected portion of a selected one of the second and third signals as an indication of respiration.

Claims

1. An apparatus, comprising:

a first port to sense a first respiration signal;

a second port to sense a second respiration signal; and

a measurement module capable of being communicatively coupled to the first and second ports to monitor the first and second respiration signals and to select a resulting signal as an indication of respiration.

2. The apparatus of claim 1, wherein the measurement module comprises a quadrapolar impedance measurement device capable of being communicatively coupled to the first and second ports.

3. The apparatus of claim 1, wherein the resulting signal includes a selected portion of the first respiration signal.

4. The apparatus of claim 1, wherein the resulting signal includes the first respiration signal, which includes an atrial respiration signal.

5. The apparatus of claim 1, wherein the resulting signal comprises a combination of selected portions of the first and second respiration signals, which include an atrial and a ventricular respiration signal, respectively.

6. The apparatus of claim 1, further comprising:

a first pair of electrodes coupled to the first port, the first pair of electrodes to be disposed within an atrium; and

a second pair of electrodes coupled to the second port, the second pair of electrodes to be disposed within a ventricle.

7. The apparatus of claim 6, wherein the first and second pairs of electrodes are each capable of propagating an injected current and sensing at least one resulting voltage.

8. A system, comprising:

an apparatus, including a first port to sense a first respiration signal, a second port to sense a second respiration signal, and a measurement module capable of being communicatively coupled to the first and second ports to monitor the first and second respiration signals and to select a resulting signal as an indication of respiration; and

a processor capable of being communicatively coupled to the apparatus.

9. The system of claim 8, wherein the first respiration signal is derived from a voltage measured between a first lead electrode coupled to the first port and one of two pacer electrodes.

10. The system of claim 9, wherein the second respiration signal is derived from a voltage measured between a second lead electrode coupled to the second port and one of the two pacer electrodes.

11. The system of claim 8, further comprising a current injection device capable of being communicatively coupled to the processor.

12. The system of claim 8, further comprising a filter module capable of being communicatively coupled to the measurement module.

13. The system of claim 8, further comprising:

a quadrapolar impedance measurement device included in the measurement module, the quadrapolar measurement device capable of measuring a voltage existing between an electrode coupled to the first port and one of two pacer electrodes, and a voltage existing between an electrode coupled to the second port and one of the two pacer electrodes.

14. The system of claim 13, wherein the resulting signal comprises a selected portion of an atrial respiration signal added to a selected portion of a ventricular respiration signal.

15. A method, comprising:

measuring a second signal responsive to a first signal;

measuring a third signal responsive to the first signal;

determining a respiration-to-cardiac ratio associated with each one of the second and third signals; and

providing a resulting signal including a correlate of a selected one of the second and third signals as an indication of respiration.

16. The method of claim 15, wherein measuring a second signal responsive to the first signal includes measuring a voltage associated with a ventricle.

17. The method of claim 16, wherein measuring a third signal responsive to the first signal includes measuring a voltage associated with an atrium.

18. The method of claim 15, wherein the first signal is a current.

19. The method of claim 18, comprising:

injecting the first signal between a lead electrode and a can electrode.

20. An article comprising a machine-accessible medium having associated data, wherein the data, when accessed, results in a machine performing:

measuring a second signal responsive to a first signal;

measuring a third signal responsive to a first signal;

determining a respiration-to-cardiac ratio associated with each one of the second and third signals; and

providing a resulting signal including a selected portion of a selected one of the second and third signals as an indication of respiration.

21. The article of claim 20, wherein providing a resulting signal including a selected portion of a selected one of the second and third signals as an indication of respiration comprises:

combining the selected portion of the selected one of the second and third signals with a correlate of the other one of the second and third signals.

22. The article of claim 20, wherein providing a resulting signal including a selected portion of a selected one of the second and third signals as an indication of respiration comprises:

selecting a correlate of the second signal as an indication of respiration if the respiration-to-cardiac ratio associated with the second signal is greater than the respiration-to-cardiac ratio associated with the third signal.

23. The article of claim 20, wherein measuring the second signal responsive to the first signal and measuring the third signal responsive to the first signal comprise:

measuring a voltage between an atrial tip electrode and a header electrode after injecting a current between an atrial ring electrode and a can electrode.

24. The article of claim 20, wherein measuring the second signal responsive to the first signal and measuring the third signal responsive to the first signal are each repeated about 20 times per second to about 120 times per second.