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Regulators of the hedgehog pathway, compositions and uses related thereto

  • US 20040127474A1
  • Filed: 12/12/2003
  • Published: 07/01/2004
  • Est. Priority Date: 01/13/1999
  • Status: Abandoned Application
First Claim
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1. A method for inhibiting an altered growth state of a cell having a ptc loss-of-function phenotype or a smoothened gain-of-function phenotype, comprising contacting the cell with a ptc agonist in a sufficient amount to inhibit the altered growth state, wherein the ptc agonist is a organic molecule having a molecular weight less than about 750 amu.

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