Method and apparatus for monitoring of diastolic hemodynamics
First Claim
1. A system, comprising:
- an acoustic sensor to sense an acoustic energy and produce an acoustic sensor signal indicative of heart sounds;
a cardiac sensing circuit to sense a cardiac signal indicative of cardiac electrical events;
a heart sound detector coupled to the acoustic sensor and the cardiac sensing circuit, the heart sound detector adapted to detect selected heart sounds based on the acoustic sensor signal and the cardiac signal;
a parameter generator coupled to the heart sound detector, the parameter generator adapted to generate values of at least one predetermined parameter related to the selected heart sounds;
a processor coupled to the parameter generator, the processor including a trending analyzer adapted to produce and analyze at least one trend related to one or more types of the selected heart sounds based on the values of the at least one predetermined parameter; and
a therapy circuit communicatively coupled to the processor, the therapy circuit adapted to deliver at least one cardiac therapy with at least one therapy parameter determined based on the at least one trend.
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Abstract
A cardiac rhythm management system provides for ambulatory monitoring of hemodynamic performance based on quantitative measurements of heart sound related parameters for diagnostic and therapeutic purposes. Monitoring of such heart sound related parameters allows the cardiac rhythm management system to determine a need for delivering a therapy and/or therapy parameter adjustments based on conditions of a heart. This monitoring also allows a physician to observe or assess the hemodynamic performance for diagnosing and making therapeutic decisions. Because the conditions of the heart may fluctuate and may deteriorate significantly between physician visits, the ambulatory monitoring, performed on a continuous or periodic basis, ensures a prompt response by the cardiac rhythm management system that may save a life, prevent hospitalization, or prevent further deterioration of the heart.
346 Citations
44 Claims
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1. A system, comprising:
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an acoustic sensor to sense an acoustic energy and produce an acoustic sensor signal indicative of heart sounds;
a cardiac sensing circuit to sense a cardiac signal indicative of cardiac electrical events;
a heart sound detector coupled to the acoustic sensor and the cardiac sensing circuit, the heart sound detector adapted to detect selected heart sounds based on the acoustic sensor signal and the cardiac signal;
a parameter generator coupled to the heart sound detector, the parameter generator adapted to generate values of at least one predetermined parameter related to the selected heart sounds;
a processor coupled to the parameter generator, the processor including a trending analyzer adapted to produce and analyze at least one trend related to one or more types of the selected heart sounds based on the values of the at least one predetermined parameter; and
a therapy circuit communicatively coupled to the processor, the therapy circuit adapted to deliver at least one cardiac therapy with at least one therapy parameter determined based on the at least one trend. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method, comprising:
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sensing an acoustic energy to produce an acoustic sensor signal indicative heart sounds;
sensing at least one cardiac signal indicative of cardiac electrical events;
detecting selected heart sounds;
generating values of at least one predetermined parameter related to the selected heart sounds and selected cardiac electrical events;
analyzing selected values of the at least one predetermined parameter, the selected values associated with one or more types of the selected heart sounds detected during a first predetermined period of time;
producing at least one trend based on the selected values of the at least one predetermined parameter; and
delivering at least one therapy with at least one parameter determined based on the at least one trend. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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32. A cardiac rhythm management system, comprising:
an implantable device including;
an acoustic sensor to sense an acoustic energy to produce an acoustic sensor signal indicative heart sounds;
a cardiac sensing circuit to sense at least one cardiac signal indicative of cardiac electrical events;
a gating module coupled to the acoustic sensor and the cardiac sensing circuit, the gating module adapted to generate heart sound detection windows each timed for detection of one of selected heart sounds based on a time of occurrence of one of selected cardiac electrical events;
a heart sound detector, coupled to the gating module, to detect the selected heart sounds;
a measurement module coupled to the heart sound detector, the measurement module adapted to generate values of at least one predetermined parameter related to the selected heart sounds; and
a therapy circuit coupled to the measurement module, to deliver a therapy based on the values of the at least one predetermined parameter. - View Dependent Claims (33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44)
Specification