Cartridge lance

• US 20040132167A1
• Filed: 01/06/2003
• Published: 07/08/2004
• Est. Priority Date: 01/06/2003
• Status: Abandoned Application

• Current Assignee: OptiScan Biomedical Corporation
• Original Assignee: Hercules Technology Growth Capital, Inc.
• Inventors: Braig, James R., Hartstein, Philip C., Rule, Peter
• Application Number:
  US10/338,061
• Publication Number:
  US 20040132167A1
• Time in Patent Office: Days
• US Class Current: 435/287.1
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150213 Venting means
• CPC Class Codes: A61B 5/150221 Valves
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150389 Hollow piercing elements, e.g. canulas, needles, for piercing the skin
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150442 Blade-like piercing elements, e.g. blades, cutters, knives, for cutting the skin
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/15087 short range, e.g. between console and disposable using implanted devices A61B5/150877
• CPC Class Codes: A61B 5/15142 Devices intended for single use, i.e. disposable
• CPC Class Codes: A61B 5/1519 comprising driving means, e.g. a spring, for propelling the piercing unit
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: G01N 21/71 thermally excited

Abstract

An analyte detection system for analysis of a body fluid is provided, comprising an analysis portion and a sample collection portion which is configured to be removably coupled to the analysis portion. The analysis portion comprises a detector configured to detect electromagnetic radiation and a source of electromagnetic radiation. The source is positioned with respect to the detector such that electromagnetic radiation emitted by the source is received by the detector. The sample collection portion comprises a housing, a lance and a sample chamber. The lance is mounted within and moveable with respect to the housing. The sample chamber is configured to be positionable, upon coupling of the sample collection portion to the analysis portion, with respect to the source and detector such that at least a portion of any electromagnetic radiation emitted by the source passes through the sample chamber prior to being received by the detector.

Claims

1. An apparatus for use in determining the concentration of an analyte in a body fluid, said apparatus comprising:

a housing;

a sample chamber;

a lance mounted within and moveable with respect to said housing toward a lance site, said sample chamber being in fluid communication with said lance site upon movement of said lance to said lance site;

said sample chamber defined by at least one inner surface, said chamber having an interior volume, all of said at least one inner surface and said interior volume being inert with respect to said body fluid;

said interior volume being no greater than about 0.5 μ

L.

2. The apparatus of claim 1, wherein said lance site is comprised of a point on the action of path of said lance at which said lance emerges from said housing.

3. The apparatus of claim 1, wherein said sample chamber is comprised of an infrared transmissive material.

4. The apparatus of claim 3, wherein said infrared transmissive material is silicon.

5. The apparatus of claim 3, wherein said infrared transmissive material is polyethylene.

6. The apparatus of claim 3, wherein said infrared transmissive material is polypropylene.

7. The apparatus of claim 3, wherein said infrared transmissive material allows for transmission of the infrared energy having specific wavelengths.

8. The apparatus of claim 1, wherein said body fluid comprises whole-blood.

9. The apparatus of claim 1, wherein said body fluid comprises blood components.

10. The apparatus of claim 1, wherein said body fluid comprises interstitial fluid.

11. The apparatus of claim 1, wherein said body fluid comprises intercellular fluid.

12. The apparatus of claim 1, further comprising a vacuum fitting in fluid communication with said sample chamber.

13. The apparatus of claim 1, wherein said determining comprises utilizing an optical technique.

14. The apparatus of claim 13, wherein said optical technique comprises a spectroscopic technique.

15. The apparatus of claim 14, wherein said spectroscopic technique is transmissive spectroscopy.

16. The apparatus of claim 15, wherein said transmissive spectroscopy is the measurement of energy transmitted from a source and passed through said sample.

17. The apparatus of claim 16, wherein said lance comprises a distal lancing member and a proximal connector.

18. The apparatus of claim 17, wherein said distal lancing member comprises a sharp cutting implement

19. The apparatus of claim 18, wherein said cutting implement is made of a rigid material.

20. The apparatus of claim 19, wherein said rigid material is metal.

21. The apparatus of claim 17, wherein said connector receives a lancing actuator which facilitates moving said lance with respect to said sample chamber toward a lancing site.

22. The apparatus of claim 18, wherein said lancing actuator forms an operative interface between an analysis portion and a sample collection portion of said apparatus.

23. An analyte detection system for analysis of a body fluid, said analyte detection system comprising:

an analysis portion comprising a detector configured to detect electromagnetic radiation, and a source of electromagnetic radiation, said source being positioned with respect to said detector such that electromagnetic radiation emitted by said source is received by said detector; and

a sample collection portion configured to be removably coupled to said analysis portion, said sample collection portion comprising;

a housing;

a lance mounted within and moveable with respect to said housing;

a sample chamber configured to be positionable, upon coupling of said sample collection portion to said analysis portion, with respect to said source and said detector such that at least a portion of any electromagnetic radiation emitted by said source passes through said sample chamber prior to being received by said detector;

said sample chamber defined by at least one inner surface, said chamber having an interior volume, all of said at least one inner surface and said interior volume being inert with respect to said body fluid;

said interior volume being no greater than about 0.5 μ

L.

24. The apparatus of claim 23, wherein said lance comprises a distal lancing member and a proximal connector.

25. The apparatus of claim 24, wherein said distal lancing member comprises a sharp cutting implement.

26. The apparatus of claim 25, wherein said cutting implement is made of a rigid material.

27. The apparatus of claim 26, wherein said rigid material is metal.

28. The apparatus of claim 26, wherein said rigid material is an infrared transmissive material.

29. The apparatus of claim 28, wherein said infrared transmissive material is silicon.

30. The apparatus of claim 24, wherein said connector receives a lancing actuator which facilitates moving said lance with respect to said sample chamber toward a lancing site.

31. The apparatus of claim 30, wherein said lancing actuator forms an operative interface between said sample collection portion and said analysis portion.

32. The apparatus of claim 23, wherein said chamber is defined by an interior surface of a lumen extending within said lance and an optical field of view between said source and said detector along the length of said lance.

33. The apparatus of claim 23, wherein said interior volume is about 0.4 μ

L or less.

34. The apparatus of claim 23, wherein said sample collection portion further comprises a vacuum fitting in fluid communication with said sample chamber.

35. The apparatus of claim 34, wherein said analysis portion further comprises a vacuum source which is in fluid communication with said vacuum fitting upon coupling of said sample collection portion to said analysis portion.

36. The apparatus of claim 23, wherein said analysis portion further comprises a vacuum source which is in fluid communication with said sample chamber upon coupling of said sample collection portion to said analysis portion.