Therapeutic agents for pigmentation and melanocyte growth inhibitory agents

• US 20040132696A1
• Filed: 12/18/2003
• Published: 07/08/2004
• Est. Priority Date: 10/19/1999
• Status: Abandoned Application

• Current Assignee: Juichiro Nakayama
• Original Assignee: Juichiro Nakayama
• Inventors: Nakayama, Juichiro
• Application Number:
  US10/737,805
• Publication Number:
  US 20040132696A1
• Time in Patent Office: Days
• US Class Current: 514/167
• CPC Class Codes: A61K 31/59 Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
• CPC Class Codes: A61K 31/593 9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
• CPC Class Codes: A61K 8/67 Vitamins
• CPC Class Codes: A61Q 19/02 for chemically bleaching or whitening the skin

Abstract

The present invention aims to provide an effective medicine for excessive proliferation of melanocytes or pigmentation. The present invention provides therapeutic agents for pigmentation and melanocyte growth inhibitory agents containing a vitamin D derivative as an active ingredient.

Claims

1. A method of treating a pigmentation disorder, comprising administering to a host in need of such a treatment a therapeutically effective amount of a vitamin D derivative of Formula (IV):

2. The method of claim 1, wherein said administering is by a systemic route.

3. The method of claim 1, wherein said amount is 1-100 μ

g/day.

4. A method of inhibiting the growth of melanocytes, comprising

administering to a host in need of such a treatment a therapeutically effective amount of a vitamin D derivative of Formula (IV):

5. The method of claim 4, wherein said administering is by a systemic route.

6. The method of claim 4, wherein said amount is 1-100 μ

g/day.