Programmed pulsed infusion methods and devices
First Claim
1. A method of infusing a fluid into a blood vessel comprising administering the fluid into the blood vessel in programmed pulses defined by programmed pulse variables comprising a fluid flow rate, a frequency, and a duration, values of the programmed pulse variables determined based at least in part on at least one of a fluid property of the fluid to be infused relevant to streaming, blood flow in the blood vessel to be infused, a catheter size, and a patient profile.
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Accused Products
Abstract
This invention disclosed herein provides methods, devices, software products, and systems for infusing a fluid into a blood vessel is provided that includes the step of administering the fluid into the blood vessel in programmed pulses. The programmed pulses generally defined by programmed pulse variables that include a fluid flow rate, a frequency, and a duration. Values of the programmed pulse variables may be determined based at least in part on a fluid property of the fluid to be infused that is relevant to streaming, blood flow in the blood vessel to be infused, a catheter size, or a patient profile.
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Citations
34 Claims
- 1. A method of infusing a fluid into a blood vessel comprising administering the fluid into the blood vessel in programmed pulses defined by programmed pulse variables comprising a fluid flow rate, a frequency, and a duration, values of the programmed pulse variables determined based at least in part on at least one of a fluid property of the fluid to be infused relevant to streaming, blood flow in the blood vessel to be infused, a catheter size, and a patient profile.
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8. The method of clam 1, wherein the fluid comprises a drug and wherein the drug is administered in programmed pulses at the duration based on a transfer rate of the drug across a blood brain barrier.
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9. The method of clam 1, wherein the fluid is a drug and wherein the drug is administered in programmed pulses at the frequency based on a rate of elimination of the drug from a brain.
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13. A programmed pulse infusion device comprising:
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a pump;
a controller with associated memory interfacing with the pump; and
a fluid reservoir containing a fluid feeding the pump, the controller providing a drive signal for the pump to deliver the fluid for infusion into a blood vessel in programmed pulses defined by programmed pulse variables comprising a fluid flow rate, a frequency, and a duration, values of the programmed pulse variables determined based at least in part on at least one of a fluid property of the fluid to be infused relevant to streaming, blood flow in the blood vessel to be infused, a catheter size, and a patient profile. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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- 24. A computer readable medium comprising program code that when executed enables a user to determine values of programmed pulse variables for infusing a fluid in a blood vessel in programmed pulses defined by the programmed pulse variables comprising a fluid flow rate, a frequency, and a duration, the values of programmed pulse variables determined at least in part on at least one of a fluid property of the fluid to be infused relevant to streaming, blood flow in the blood vessel to be infused, a catheter size, and a patient profile.
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30. A computer system comprising a controller and associated computer memory, and a computer readable medium accessible to the controller, stored on the computer readable medium at least one database comprising at least one of:
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data of fluid properties for a fluid that may be infused into a blood vessel relevant to streaming; and
values of programmed pulse variables based on at least one of a patient profile, a blood flow rate in the blood vessel , a fluid property for the fluid relevant to streaming, and a catheter size, the database accessed to enable users to determine the values of programmed pulse variables for infusing the fluid in the blood vessel in programmed pulses defined by the programmed pulse variables comprising a fluid flow rate, a frequency, and a duration. - View Dependent Claims (31, 32, 33, 34)
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Specification