Method of measuring biological component concentration and apparatus therefor
First Claim
1. A method of calculating a biological component density of a subject, said method comprising the steps of:
- irradiating a light of NIR (near infrared) spectrum to a skin of the subject;
receiving said light of NIR reflected from said skin to obtain NIR spectrum data thereof;
substituting said NIR spectrum data into a predetermined calibrating equation to obtain a biological component density such as glucose density of said subject;
characterized in that (wherein) preparing a plurality of the calibrating equations which are different from each other and are each specific to each of a plural groups which are classified in terms of a skin thickness parameter indicative of a skin thickness with respect to individuals of a species to which said subject belongs;
determining said skin thickness parameter of the subject with a non-invasive technique and identifying the group of the subject in accordance with the determined skin thickness parameter, deriving one of said calibrating equations in match with the identified group in order to calculate the biological component density of the subject.
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Abstract
A method for calculating a biological component density of this invention comprises steps of irradiating a light of NIR spectrum to a skin of a subject, receiving the light of NIR reflected from the skin to obtain NIR spectrum data thereof, and substituting the NIR spectrum data into a predetermined calibrating equation to obtain a biological component density of the subject such as glucose density. This invention is characterized by preparing a plurality of the calibrating equations which are different from each other and are specific to each of plural groups which are classified in terms of a skin thickness parameter indicative of a skin thickness with respect to individuals of a species to which the subject belongs, determining the skin thickness parameter of the subject with a non-invasive technique and identifying the group of the subject in accordance with the determined skin thickness parameter, and deriving one of the calibrating equations in match with the identified group in order to calculate the biological component density of the subject.
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Citations
12 Claims
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1. A method of calculating a biological component density of a subject, said method comprising the steps of:
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irradiating a light of NIR (near infrared) spectrum to a skin of the subject;
receiving said light of NIR reflected from said skin to obtain NIR spectrum data thereof;
substituting said NIR spectrum data into a predetermined calibrating equation to obtain a biological component density such as glucose density of said subject;
characterized in that (wherein) preparing a plurality of the calibrating equations which are different from each other and are each specific to each of a plural groups which are classified in terms of a skin thickness parameter indicative of a skin thickness with respect to individuals of a species to which said subject belongs;
determining said skin thickness parameter of the subject with a non-invasive technique and identifying the group of the subject in accordance with the determined skin thickness parameter, deriving one of said calibrating equations in match with the identified group in order to calculate the biological component density of the subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A device for calculating a biological component density of a subject, which comprises:
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a light source generating a light having a NIR (near infrared) spectrum;
an incident guide directing said light to a skin of said subject;
a reflective guide directing the NIR spectrum reflected back from within said skin;
a sensor receiving said NIR spectrum through said reflective guide to provide NIR data thereof;
a processing unit which substitutes said NIR data into a predetermined calibrating equation to calculate the biological component density such as glucose density of said subject, characterized in that (wherein) said device further includes;
a skin thickness memory storing a plurality of the calibrating equations which are different from each other and which are each specific to each of a plural groups classified in terms of a skin thickness parameter indicative of a skin thickness with respect to individuals of a species to which said subject belongs; and
a means for determining the skin thickness parameter with an non-invasive technique to identify the group of the subject in accordance with the determined skin thickness parameter;
said processing unit operating to derive one of said calibrating equations from said skin thickness memory in match with the identified group in order to calculate the biological component density of the subject. - View Dependent Claims (10, 11, 12)
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Specification