Methods of achieving lung volume reduction with removable anchored devices

• US 20040143282A1
• Filed: 12/23/2003
• Published: 07/22/2004
• Est. Priority Date: 05/17/2002
• Status: Active Grant

• Current Assignee: Gyrus ACMI, Inc. (Olympus Corporation)
• Original Assignee: Spiration, Inc. (Olympus Corporation)
• Inventors: Park, Mia, Yi, Seung, Rimbaugh, Jenni, DeVore, Lauri J., Corcoran, Dean T., Dillard, David H., Gonzalez, Hugo X.
• Granted Patent: US 7,842,061 B2
• Time in Patent Office: Days
• US Class Current: 606/191
• CPC Class Codes: A61B 17/12104 in an air passage
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/00809 Lung operations
• CPC Class Codes: A61F 2/2476 Valves implantable in the body not otherwise provided for
• CPC Class Codes: A61F 2002/043 Bronchi

Abstract

An intra-bronchial device placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes a support structure, an obstructing member carried by the support structure that reduces ventilation to the lung portion by preventing air from being inhaled into the lung portion, and at least one anchor carried by the support structure that anchors the obstruction device within the air passageway. The anchor may engage the air passageway wall by piercing or friction, include a stop dimensioned for limiting the piercing of the air passageway wall, and may be releasable from the air passageway for removal of the intra-bronchial device. The anchors may be carried by a peripheral portion of the support structure, or by a central portion of the support structure. The obstructing member may be a one-way valve.

Claims

1. An intra-bronchial device for placement in an air passageway of a patient to collapse a lung portion associated with the air passagewy, the device comprising:

a support structure comprising a central member extending through an axial center of the device, the central member configured to be engaged by a removal device;

an obstructing member carried by the support structure that prevents air from being inhaled into the lung portion to collapse the lung portion; and

at least one anchor carried by the support structure that anchors the obstruction device within the air passageway when the anchor is deployed.

2. The intra-bronchial device of claim 1, wherein the support structure comprises material having memory of an original shape, and resiliency to return the material to that shape.

3. The intra-bronchial device of claim 1, wherein the central member comprises an aperture configured to be engaged by a removal device.

4. The intra-bronchial device of claim 1, wherein the obstructing member is an air impermeable membrane.

5. The intra-bronchial device of claim 4, wherein the support structure, the central rod and the membrane form a substantially umbrella-shaped device.

6. An air passageway obstructing device comprising:

frame means for forming a support structure;

flexible membrane means for obstructing airflow within the air passageway, carried by the support structure; and

anchoring means to anchor the air passageway obstructing device, carried by the support structure, the frame means being expandable to an expanded state within an air passageway to support the membrane means and the anchoring means, the anchoring means being releasable for removal of the device from the air passageway.

7. The air passageway obstructing device of claim 6, wherein the frame means further comprises a central post configured to be engaged by a removal device.

8. The air passageway obstructing device of claim 7, wherein the membrane means is supported on the support structure such that it forms a concave side and a convex side.

9. The air passageway obstructing device of claim 8, wherein the membrane is configured to permit fluid flow from the convex side to the concave side, while precluding air from flowing from the concave side to the convex side.

10. An air passageway obstructing device for use in occluding inspiratory airflow in an airway of a lung, the device comprising an expandable frame comprising a central rod having a proximal end and a distal end with a plurality of strut members extending proximally and radially outwards from a point of attachment of the strut members on the rod, and a membrane supported on the strut members, wherein the membrane is configured to be impermeable to airflow.

11. The device of claim 10, wherein the device is configured to permit fluid flow in an expiratory direction along a path between the membrane and an air passageway wall.

12. The device of claim 10, further comprising at least one anchor member attached to the central rod and extending radially and distally therefrom.

13. The device of claim 11, wherein the anchor member is attached to a proximal portion of the central rod.

14. The device of claim 11, wherein the anchor member is configured to puncture a tissue of an airway wall to a controlled depth.

15. The device of claim 10, wherein a plane which intersects proximal ends of the strut members lies distal to the proximal end of the central rod.

16. The device of claim 11, wherein the central rod comprises a proximal end configured to be engaged by a retrieval device.

17. The device of claim 16, wherein the strut members are configured to return to a radially expanded position after being compressed radially to such a degree that they contact the central rod.

18. The device of claim 10, wherein proximal ends of the strut members are bent radially inwards.