Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
First Claim
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1. A composition comprising a Cox-2 inhibitor and a 5-HT1A receptor modulator.
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Abstract
Compositions and methods to treat or prevent pain, inflammation, or inflammation-related disorder, as well as a neurologic disorder involving neurodegrneration in a subject that is in need of such prevention or treatment involve a combination of a Cox-2 inhibitor and a 5-HT1A receptor modulator.
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26 Claims
- 1. A composition comprising a Cox-2 inhibitor and a 5-HT1A receptor modulator.
- 12. A method for the treatment or prevention of pain, inflammation, or inflammation-related disorder in a subject in need thereof, comprising administering to the subject a Cox-2 inhibitor and a 5-HT1A receptor modulator.
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24. A pharmaceutical composition for the treatment or prevention of pain, inflammation, or inflammation-related disorder, the pharmaceutical composition comprising a Cox-2 inhibitor, a 5-HT1A receptor modulator, and a pharmaceutically-acceptable excipient.
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25. A kit that is suitable for use in the treatment or prevention of pain, inflammation, or inflammation-related disorder wherein the kit comprises a first dosage form comprising a Cox-2 inhibitor and a second dosage form comprising a 5-HT1A receptor modulator, in quantities which comprise a therapeutically effective amount of the compounds for the treatment, prevention or inhibition of pain, inflammation, or an inflammation-related disorder.
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26. A method for the prevention or treatment of a neurologic disorder involving neurodegeneration in a subject that is in need of such prevention or treatment, the method comprising administering to the subject a Cox-2 inhibitor and a 5-HT1A receptor modulator.
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