Antimicrobial lenses, processes to prepare them and methods of their use
First Claim
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1. An antimicrobial ophthalmic lens comprising a metal salt and having a percent haze of less than about 200%.
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Accused Products
Abstract
This invention relates to antimicrobial lenses containing metals and methods for their production.
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Citations
44 Claims
- 1. An antimicrobial ophthalmic lens comprising a metal salt and having a percent haze of less than about 200%.
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22. An antimicrobial lens comprising a metal complex wherein the molar solubility of the metal ions in pure water at about 25 °
- C. is greater than or equal to about 2.00×
10−
30moles/L. - View Dependent Claims (23, 24, 25)
- C. is greater than or equal to about 2.00×
- 26. A method of reducing the adverse events associated with microbial colonization on a lens placed in the ocular regions of a mammal comprising, placing an antimicrobial lens comprising a metal salt on the eye of a mammal.
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28. A method of producing an antimicrobial lens comprising a metal salt wherein the method comprises mixing the metal salt with lens components to make a lens formulation and forming the lens from said lens formulation.
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29. A method of preparing an antimicrobial lens comprising a metal salt, wherein the method comprises, the steps of
(a) mixing a salt precursor with a lens formulation; -
(b) forming the lens with the product of step (a); and
(c) treating the lens with a metal agent. - View Dependent Claims (30, 31, 32, 44)
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33. A method of preparing an antimicrobial lens comprising a metal salt, wherein the method comprises the steps of
(a) mixing a metal precursor with an lens formulation; -
(b) forming the lens; and
(c) treating the lens with an anion precursor. - View Dependent Claims (34, 35)
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36. A method of preparing an antimicrobial lens comprising a metal salt, wherein the method comprises the steps of
(a) treating a cured lens with a salt precursor; (b) treating the lens of step (a) with a metal agent under conditions to produce an antimicrobial lens having less than about 200% haze. - View Dependent Claims (42)
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37. A method of preparing an antimicrobial lens comprising a metal salt, wherein the method comprises the steps of
(b) treating cured lens of with a metal agent. (b) treating the lens of step (a) with a salt precursor.
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39. A method of preparing an antimicrobial lens comprising a metal salt, wherein the method comprises the steps of
(a) mixing a metal with a lens formulation; -
(b) forming the lens;
(c) treating the lens of step (b) with an oxidizing agent; and
(d) treating the lens of step (c) with an anion precursor.
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Specification