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Systemic immune activation method using nucleic acid-lipid complexes

  • US 20040157791A1
  • Filed: 02/05/2004
  • Published: 08/12/2004
  • Est. Priority Date: 06/25/1998
  • Status: Abandoned Application
First Claim
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1. A method to elicit an immunogen-specific immune response and a systemic, non-specific immune response in a mammal, comprising administering to said mammal a therapeutic composition by a route of administration selected from the group consisting of intravenous and intraperitoneal, said therapeutic composition comprising:

  • (a) a liposome delivery vehicle; and

    , (b) a recombinant nucleic acid molecule comprising an isolated nucleic acid sequence encoding an immunogen, said nucleic acid sequence being operatively linked to a transcription control sequence.

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