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Biomolecule analysis by rolling circle amplification and SERS detection

  • US 20040161750A1
  • Filed: 02/14/2003
  • Published: 08/19/2004
  • Est. Priority Date: 02/14/2003
  • Status: Active Grant
First Claim
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1. A method comprising:

  • a) attaching one or more target biomolecules to a substrate;

    b) using a first primer to produce one or more rolling circle amplification (RCA) products;

    c) detecting each amplification product by Raman spectroscopy; and

    d) identifying one or more target biomolecules by the presence of one or more amplification products.

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