Non-invasive transudate extraction
First Claim
1. A transudate extraction device for non-invasive extraction of transudate through a target area of a skin barrier of an organism subjected to sufficient ultrasonic energy to induce transudation therethrough, the device including at least:
- a contacting means for contacting said target area to receive transudate therefrom, a transudate collection chamber in open communication with said contacting means to receive transudate therefrom, circulating means for circulating transudate within said collection chamber to thereby create and maintain a concentration gradient through the skin of a said test subject, said collection chamber having a discharge opening through which exudate collected therein can be discharged.
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Accused Products
Abstract
A transudate extraction device (1) for non-invasive extraction of transudate through a target area of a skin barrier of an organism subjected to sufficient ultrasonic energy from a generator (2) to induce transudation therethrough, the device including at least: a contacting means (3) for contacting said target area to receive transudate therefrom, a transudate collection chamber (6) in open communication with said contacting means to receive transudate therefrom, circulating means for circulating transudate within said collection chamber by, for example having a fluid flow (12) through an inlet port (8) and out an outlet port (9) to thereby create and maintain a concentration gradient through the skin of a said test subject, said collection chamber having a discharge opening (9) through which exudate collected therein can be discharged.
48 Citations
35 Claims
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1. A transudate extraction device for non-invasive extraction of transudate through a target area of a skin barrier of an organism subjected to sufficient ultrasonic energy to induce transudation therethrough, the device including at least:
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a contacting means for contacting said target area to receive transudate therefrom, a transudate collection chamber in open communication with said contacting means to receive transudate therefrom, circulating means for circulating transudate within said collection chamber to thereby create and maintain a concentration gradient through the skin of a said test subject, said collection chamber having a discharge opening through which exudate collected therein can be discharged. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 35)
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17. A method for non-invasively extracting transudate through a skin barrier of an organism, which includes at least the steps of:
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treating a target area of a said skin barrier with a sufficient concentration of ultrasonic energy to induce transudation therethrough;
collecting said transudate thereby produced in a dynamic flow of fluid, said dynamic flow being controlled so as to provide a concentration gradient in a direction which induces continuing transudation through said skin barrier, and recovering transudate from said dynamic flow. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34)
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Specification