Sutures and coatings made from therapeutic absorbable glass
First Claim
Patent Images
1. A coating composition for a surgical device comprising:
- water-soluble glass and a polymer selected from the group consisting of a biocompatible bioabsorbable polymer and biocompatible non-bioabsorbable polymer, wherein the coating composition is adapted to coat the surgical device.
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Abstract
Sutures fabricated from and/or coated with compositions including water-soluble glass are described herein. Pledgets containing water-soluble glass within the interstices of the pledget and/or coated with compositions including water-soluble glass are also described herein. The water-soluble glass optionally includes a therapeutic agent, e.g., silver to promote wound repair.
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Citations
79 Claims
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1. A coating composition for a surgical device comprising:
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water-soluble glass and a polymer selected from the group consisting of a biocompatible bioabsorbable polymer and biocompatible non-bioabsorbable polymer, wherein the coating composition is adapted to coat the surgical device. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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- 19. A suture coated with a coating composition, the coating composition comprising water-soluble glass and a polymer selected from the group consisting of a biocompatible bioabsorbable polymer and biocompatible non-bioabsorbable polymer.
- 29. A monofilament suture comprising therapeutic water-soluble glass and a polymer selected from the group consisting of biocompatible bioabsorbable polymer and biocompatible non-bioabsorbable polymer.
- 34. A multifilament suture comprising filaments fabricated from biocompatible water-soluble glass.
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40. A method for preparing a suture having therapeutic activity comprising:
applying to the suture a coating composition including therapeutic water-soluble glass containing a therapeutically effective amount of a therapeutic agent. - View Dependent Claims (41, 45, 46, 48, 53, 54, 55)
- 47. A method of preparing a coating composition for a surgical device comprising dispersing water-soluble glass and a polymer selected from the group consisting of biocompatible bioabsorbable polymer or biocompatible non-bioabsorbable polymer in a suitable solvent, wherein the coating composition is adapted to coat the surgical device.
- 56. A pledget comprising water-soluble glass.
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72. A method for preparing a pledget having therapeutic activity comprising:
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providing therapeutic water-soluble glass;
providing a pledget; and
incorporating the therapeutic water-soluble glass into the pledget. - View Dependent Claims (73, 74, 75, 76, 77, 78, 79)
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Specification