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Molecular microarrays and methods for production and use thereof

  • US 20040171053A1
  • Filed: 03/05/2004
  • Published: 09/02/2004
  • Est. Priority Date: 11/02/1999
  • Status: Abandoned Application
First Claim
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1. A microarray comprising:

  • (a) a substrate, wherein the substrate is derivatized with either;

    i) a first compound comprising a first functional group, and at least one layer of a cross-linking compound comprising multiple second functional groups, or ii) a first compound comprising a first functional group, and a polymeric film comprising multiple second functional groups; and

    (b) either;

    i) a population of at least one entity of interest, wherein the population of at least one entity of interest is associated with a distinct address on the substrate through coupling of the entities and the second functional groups, or ii) a population of microparticles, wherein the population of microparticles has at least one entity of interest coupled thereto, and wherein the population of microparticles is associated with a distinct address on the substrate through coupling of the second functional groups with the microparticles, such that the at least one entity of interest occupies a distinct address on the substrate.

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