Method of bottle formation and storing a pharmaceutical formulation
First Claim
1. A container for product protection and identification, said product comprising an ophthalmic formulation including chlorine dioxide, said container comprising:
- a bottle formed from resins comprising polypropylene, said resins including a first resin consisting of natural polypropylene;
an ultraviolet blocker in said bottle to absorb ultraviolet light at wavelengths below about 312 nm;
a second resin consisting of polypropylene and a set of dyestuffs present in said bottle in an amount sufficient to absorb most visible and ultraviolet wavelength less than about 420 nm; and
a third resin consisting of polypropylene and a set of dyestuffs present in said bottle in an amount sufficient to absorb most visible wavelengths greater than about 500 nm, the second and third resin dyestuffs sets allowing transmission of visible blue wavelengths for enabling visual inspection of the product contained in said bottle and providing a product identifying color to said bottle.
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Abstract
A container for product integrity and identification includes a bottle formed from a resin comprising polypropylene and a first set of dye stuffs present in the bottle in an amount sufficient to absorb visible and ultraviolet wavelengths which may cause product degradation. An ultraviolet blocking agent is present to absorb ultraviolet wavelengths which may cause product degradation. A second set of dyestuffs is present in the bottle in an amount sufficient to provide an identifying blue color of the bottle while enabling sufficient transmission of the light for visual inspection of the product contained in the bottle.
25 Citations
12 Claims
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1. A container for product protection and identification, said product comprising an ophthalmic formulation including chlorine dioxide, said container comprising:
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a bottle formed from resins comprising polypropylene, said resins including a first resin consisting of natural polypropylene;
an ultraviolet blocker in said bottle to absorb ultraviolet light at wavelengths below about 312 nm;
a second resin consisting of polypropylene and a set of dyestuffs present in said bottle in an amount sufficient to absorb most visible and ultraviolet wavelength less than about 420 nm; and
a third resin consisting of polypropylene and a set of dyestuffs present in said bottle in an amount sufficient to absorb most visible wavelengths greater than about 500 nm, the second and third resin dyestuffs sets allowing transmission of visible blue wavelengths for enabling visual inspection of the product contained in said bottle and providing a product identifying color to said bottle. - View Dependent Claims (2, 3, 4, 5)
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6. A container for product protection and identification, said product comprising an ophthalmic formulation including chlorine dioxide, said container comprising:
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a bottle formed from resins comprising of polypropylene, said resins including;
a first resin consisting of natural polypropylene;
a second resin consisting of polypropylene and a set of dyestuffs present in said bottle in an amount sufficient to absorb most visible and ultraviolet wavelengths causing degradation of chlorine dioxide;
an ultraviolet light blocking agent to remove ultraviolet wavelengths causing degradation of chlorine dioxide; and
a third resin consisting of polypropylene and a set of dyestuffs present in said bottle in an amount sufficient to provide an identifying blue color to said bottle while enabling sufficient transmission of light for visual inspection of the product contained in said bottle. - View Dependent Claims (7, 8, 9)
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10. A container for product protection and identification, said product comprising an ophthalmic formulation including chlorine dioxide, said container comprising:
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a bottle formed from resins comprised of polypropylene, said bottle having a cylindrical shape, a volume of between about 5 ml and about 15 ml and. walls having a thickness of between about 0.5 mm and about 2 mm for enabling dropwise squeeze dispensing of the product from the bottle, said resins including a first resin consisting of natural polypropylene;
a second resin consisting of polypropylene and a set of dyestuffs present in said bottle in an amount sufficient to absorb most visible and ultraviolet wavelengths less than about 420 nm;
an ultraviolet blocking agent to absorb ultraviolet wavelengths less than about 312 nm; and
a third resin consisting of polypropylene and a set of dyestuffs present in said bottle in an amount sufficient to absorb most visible wavelengths greater than about 500 nm, the second and third resin dyestuffs sets allowing transmission of visible blue wavelengths for enabling visual inspection of the product contained in said bottle and providing a product identifying color to said bottle. - View Dependent Claims (11)
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12. A method for storing a pharmaceutical formulation comprising chlorine dioxide, said method comprising the steps of:
forming a bottle of a resin comprising polypropylene with a first set of dyestuffs present in said bottle in an amount sufficient to absorb visible and ultraviolet wavelengths less than about 420 nm, an ultraviolet blocking agent to absorb ultraviolet wavelengths less than about 312 nm, a second set of dyestuffs present in said bottle in an amount sufficient to absorb visible wavelengths greater than about 500 n, the first and second dyestuffs sets allowing transmission of visible blue wavelengths for enabling visual inspection of the product contained in said bottle and providing a product identifying color to said bottle, disposing the pharmaceutical formulation in said bottle; and
sealing said bottle.
Specification