Method and test strip for determining glucose in blood
First Claim
1. A method for determining glucose concentration in a sample of whole blood, the method comprising (a) providing a test strip having a sample side and a reaction side, the test strip being adapted to accept the sample on the sample side and pass it toward the reaction side, said test strip supporting a testing reagent, said testing reagent comprising a color indicator system that changes color to indicate the presence of glucose in the sample, said test strip further having a polymer on at least the reaction side, said polymer increasing the opacity of the reaction side of the test strip, (b) applying the blood sample to the sample side of the test strip, and, (c) measuring the change in color of the testing side to determine the glucose concentration in the blood.
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Accused Products
Abstract
A reagent strip for measuring the concentration of glucose in whole blood has a polymer on at least one side thereof to increase the opacity thereof, thereby reducing the effect of hematocrit on the glucose determination.
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Citations
20 Claims
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1. A method for determining glucose concentration in a sample of whole blood, the method comprising
(a) providing a test strip having a sample side and a reaction side, the test strip being adapted to accept the sample on the sample side and pass it toward the reaction side, said test strip supporting a testing reagent, said testing reagent comprising a color indicator system that changes color to indicate the presence of glucose in the sample, said test strip further having a polymer on at least the reaction side, said polymer increasing the opacity of the reaction side of the test strip, (b) applying the blood sample to the sample side of the test strip, and, (c) measuring the change in color of the testing side to determine the glucose concentration in the blood.
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11. A test strip for measuring glucose concentration in a sample of whole blood that contains red blood cells, comprising
(a) a porous membrane having a sample side and a reaction side, the membrane being adapted to accept the sample on the sample side and pass it toward the reaction side, (b) a testing reagent supported by the membrane, said testing reagent comprising a color indicator system that changes color to indicate the presence of glucose in the sample, and (c) a polymer on at least the reaction side of the membrane, said polymer increasing the opacity of the reaction side of the membrane.
Specification