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Afinity biosensor for monitoring biological process

  • US 20040186359A1
  • Filed: 01/09/2004
  • Published: 09/23/2004
  • Est. Priority Date: 07/09/2001
  • Status: Abandoned Application
First Claim
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1. An optical fiber surface plasmon resonance (SPR) biosensor for observation of a biological marker in a biological fluid wherein said biological marker is a first member of a binding pair, and said biosensor comprises:

  • a. an SPR probe surface having immobilized thereon a second member of said binding pair;

    b. a spectrophotometric means for receiving a first signal from said probe surface and a second signal from said implanted probe surface, said second signal being received at a time after binding of said first and second members of said binding pair on said probe surface; and

    c. means for comparing properties of said first received signal and said second received signal to determine the presence of said biological marker.

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