Subcutaneous implantable medical devices with anti-microbial agents for chronic release
First Claim
1. A method of providing anti-microbial protection in a subcutaneous pocket in which an implantable medical device (IMD) having a predetermined IMD shape is implanted comprising:
- providing an anti-microbial component that conforms to the IMD shape and is selectively attachable to and detachable from the IMD;
attaching the anti-microbial component to the IMD; and
implanting the IMD and the anti-microbial component within the subcutaneous pocket.
1 Assignment
0 Petitions
Accused Products
Abstract
An anti-microbial component of the IMD that is exposed to body fluids in the pocket is compounded of an anti-microbial metal ion zeolite that elutes metal ions in concentrations exhibiting anti-microbial activity over a substantial period of time of implantation is disclosed. The anti-microbial component is physically attached to the IMD to be retained in close proximity and in a stable location in the subcutaneous pocket. In another embodiment, the anti-microbial component conforms to the shape of the IMD and is attachable to and detachable from the IMD. In another embodiment, the polymeric component includes a connector header of an IPG or a monitor, or a connector sleeve or the sealing rings of a proximal connector assembly of an electrical medical lead coupled with an IPG or monitor that are located in the subcutaneous pocket or in the backing of a subcutaneously implanted cardioversion/defibrillation (C/D) electrode.
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Citations
53 Claims
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1. A method of providing anti-microbial protection in a subcutaneous pocket in which an implantable medical device (IMD) having a predetermined IMD shape is implanted comprising:
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providing an anti-microbial component that conforms to the IMD shape and is selectively attachable to and detachable from the IMD;
attaching the anti-microbial component to the IMD; and
implanting the IMD and the anti-microbial component within the subcutaneous pocket. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method of providing anti-microbial protection in a subcutaneous pocket in which an implantable medical device (IMD) having a biocompatible polymeric component is implanted comprising:
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forming at least a portion of the polymeric component of the IMD with an anti-microbial IMD component; and
implanting the IMD with the anti-microbial IMD component within the subcutaneous pocket. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. Apparatus for providing anti-microbial protection in a subcutaneous pocket in which an implantable medical device (IMD) having a predetermined IMD shape is implanted comprising:
an anti-microbial component shaped to conform to the shape of the IMD; and
means for attaching the anti-microbial component to the IMD.- View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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37. A apparatus for providing anti-microbial protection in a subcutaneous pocket in which an implantable medical device (IMD) is implanted comprising:
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an IMD housing formed at least in part of a biocompatible polymeric component; and
an anti-microbial agent incorporated into the biocompatible polymeric component to provide an anti-microbial IMD component providing anti-microbial activity by elution of anti-microbial agent into body fluids. - View Dependent Claims (38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53)
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Specification