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Delivery of compounds for the treatment of migraine through an inhalation route

  • US 20040191180A1
  • Filed: 01/27/2004
  • Published: 09/30/2004
  • Est. Priority Date: 05/24/2001
  • Status: Active Grant
First Claim
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1. A composition for delivery of rizatriptan consisting of a condensation aerosol a) formed by volatilizing a thin layer of rizatriptan on a solid support, having the surface texture of a metal foil, to a temperature sufficient to produce a heated vapor of rizatriptan and condensing the heated vapor of rizatriptan to form condensation aerosol particles, b) wherein said condensation aerosol particles are characterized by less than 5% rizatriptan degradation products, and c) the condensation aerosol has an MMAD of less than 3 microns.

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