Tissue collection device and methods
First Claim
1. A biological tissue collection device, comprising:
- a housing having a fluid-retaining inner chamber adapted to retain a bioimplantable, fluid permeable tissue scaffold in such a way that the scaffold separates the fluid-retaining inner chamber into a first chamber and a second chamber; and
a driver mechanism coupled to the housing and effective to create a force within the housing to displace fluid disposed within the second chamber to the first chamber and thereby disperse any biological tissue deposited on the tissue scaffold within the fluid, wherein removal of the force enables the fluid to return to the second chamber and thereby deposit the biological tissue onto the tissue scaffold.
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Accused Products
Abstract
A biological tissue collection device is provided having a housing with a fluid-retaining inner chamber adapted to retain a bioimplantable, fluid permeable tissue scaffold. The scaffold is preferably retained in the housing in such a way that the scaffold separates the fluid-retaining inner chamber into a first chamber and a second chamber. The collection device further includes a driver mechanism coupled to the housing and effective to create a force within the housing to displace fluid disposed within the second chamber to the first chamber. As the fluid is displaced, any biological tissue deposited on the tissue scaffold is dispersed within the fluid. Removal of the force enables the fluid to return to the second chamber and thereby deposit the tissue onto the tissue scaffold. In an exemplary embodiment, the tissue is deposited evenly onto the tissue scaffold.
106 Citations
42 Claims
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1. A biological tissue collection device, comprising:
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a housing having a fluid-retaining inner chamber adapted to retain a bioimplantable, fluid permeable tissue scaffold in such a way that the scaffold separates the fluid-retaining inner chamber into a first chamber and a second chamber; and
a driver mechanism coupled to the housing and effective to create a force within the housing to displace fluid disposed within the second chamber to the first chamber and thereby disperse any biological tissue deposited on the tissue scaffold within the fluid, wherein removal of the force enables the fluid to return to the second chamber and thereby deposit the biological tissue onto the tissue scaffold. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A biological tissue collection device, comprising:
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a housing having a proximal chamber, a distal chamber, and a tissue scaffold retaining member disposed therebetween;
a driver mechanism coupled to the proximal chamber and effective to create a fluid driving force within the first and second chambers; and
a driver release mechanism formed in one of the first and second chambers and that is effective to release the force applied by the driver mechanism. - View Dependent Claims (32, 33, 34, 35)
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36. A method of preparing a tissue scaffold, comprising the steps of:
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providing a biological tissue collection device having a housing having a fluid-retaining inner chamber;
a bioimplantable, fluid permeable tissue scaffold disposed within the fluid-retaining inner chamber of the housing such that the tissue scaffold separates the fluid-retaining inner chamber into a first chamber and a second chamber, and a driver mechanism coupled to the housing and effective to create a force within the housing;
delivering a biological tissue-containing fluid into the first chamber, wherein the biological tissue is deposited onto the tissue scaffold and the fluid flows through the tissue scaffold and into the second chamber;
activating the driver mechanism to cause fluid to be displaced from the second chamber and into the first chamber, whereby any biological tissue deposited on the tissue scaffold is dispersed within the fluid;
releasing the driver mechanism to enable the fluid to return to the second chamber and thereby deposit the biological tissue onto the tissue scaffold. - View Dependent Claims (37, 38, 39, 40, 41, 42)
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Specification