Treatment of movement disorders with drug therapy
First Claim
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1. A method of treating a patient with a movement disorder, comprising:
- providing at least one miniature leadless stimulator for controlling delivery of at least one stimulus via at least one infusion outlet, wherein the at least one stimulus comprises stimulation via at least one drug delivered through the at least one outlet;
implanting the at least one stimulator entirely or substantially in the carotid sheath; and
, using the stimulator, applying the at least one stimulus to at least one vagus nerve in order to at least in part alleviate the movement disorder of the patient being treated.
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Abstract
Introducing one or more stimulating drugs to the vagus nerve and/or one or more branches of the vagus nerve to treat movement disorders uses at least one implantable system control unit (SCU) with an implantable pump with at least one infusion outlet. Optional electrical stimulation may additionally be supplied by an implantable signal/pulse generator (IPG) with one or more electrodes. In certain embodiments, a single SCU provides one or more stimulating drugs and the optional electrical stimulation. In some embodiments, one or more sensed conditions are used to adjust stimulation parameters.
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Citations
20 Claims
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1. A method of treating a patient with a movement disorder, comprising:
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providing at least one miniature leadless stimulator for controlling delivery of at least one stimulus via at least one infusion outlet, wherein the at least one stimulus comprises stimulation via at least one drug delivered through the at least one outlet;
implanting the at least one stimulator entirely or substantially in the carotid sheath; and
,using the stimulator, applying the at least one stimulus to at least one vagus nerve in order to at least in part alleviate the movement disorder of the patient being treated. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method of treating a patient with a movement disorder, comprising:
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providing at least one system control unit that generates stimulating pulses in accordance with prescribed parameters, which stimulating pulses are infusion pulses;
providing at least one catheter connected to the at least one system control unit, which catheter includes at least one discharge portion;
implanting the at least one catheter discharge portion adjacent to at least one vagus nerve to be stimulated;
implanting the at least one system control unit at a location remote from the at least one tissue to be stimulated;
tunneling the catheter subcutaneously to the system control unit location; and
delivering via the infusion pulses at least one drug to the at least one vagus nerve, thereby affecting a movement disorder in order to at least in part alleviate the movement disorder of the patient being treated. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification