Methods and apparatus for treating aneurysms and other vascular defects

• US 20040193246A1
• Filed: 03/25/2003
• Published: 09/30/2004
• Est. Priority Date: 03/25/2003
• Status: Abandoned Application

• Current Assignee: Microvention Incorporated (Terumo Corporation)
• Original Assignee: Microvention Incorporated (Terumo Corporation)
• Inventors: Ferrera, David A.
• Application Number:
  US10/400,138
• Publication Number:
  US 20040193246A1
• Time in Patent Office: Days
• US Class Current: 623/1.15
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/885 comprising a coil including a plurality of spiral or helical sections with alternate directions around a central axis
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/9517 handle assemblies therefor
• CPC Class Codes: A61F 2/954 for placing stents or stent-grafts in a bifurcation
• CPC Class Codes: A61F 2002/825 having longitudinal struts

Abstract

Devices and methods are disclosed for placing a barrier across the neck of a vascular aneurysm, and specifically across the neck of a cerebrovascular aneurysm. The barrier is a stent or neck bridge that completely or partially blocks the flow of blood into the aneurysm and, further, prevents the migration of embolic coils out of the aneurysm and into the parent vessel. The neck bridge or stent of the present invention comprises elements for superior flexibility and stability when placed within the parent vessel. The neck bridge or stent of the present invention is loaded into the catheter by either being rolled tightly and sheathed or stretched to permit loading into the delivery catheter in a small, highly flexible configuration that may be advanced through the cerebrovasculature to pathological aneurysms.

Claims

1. An implantable device for bridging the neck of an aneurysm, comprising:

a plurality of circumferential bars, and

a plurality of longitudinal bars,

wherein the longitudinal bars further comprise notches or bends to improve flexibility.

2. The stent of claim 1 wherein the circumferential bars are disposed orthogonally to the longitudinal axis of the stent.

3. The stent of claim 1 wherein the circumferential bars are disposed in a spiral pattern relative to the longitudinal axis of the stent.

4. The stent of claim 1 wherein the circumferential bars are disposed at an angle other than 90 degrees relative to the longitudinal axis of the stent.

5. The stent of claim 1 wherein the distance between circumferential bars is greater at the ends of the stent than toward the center of the stent.

6. The stent of claim 1 wherein the width of the circumferential bars is greater toward the center of the stent than at the ends of the stent.

7. The stent of claim 1 wherein the width of the longitudinal bars is greater toward the center of the stent than at the ends of the stent.

8. The stent of claim 1 wherein at least a portion of the circumferential bars are coated with a swellable hydrogel.

9. The stent of claim 1 wherein at least a portion of the longitudinal bars are coated with a swellable hydrogel.

10. The stent of claim 1 wherein the axially central circumferential or longitudinal bars are coated with a swellable hydrogel.

11. The stent of claim 1 wherein one or more of the longitudinal bars is Z-folded or bent.

12. The stent of claim 11 wherein the Z-folded or bent longitudinal bars are fabricated from shape-memory alloy.

13. The stent of claim 11 wherein the Z-folded or bent longitudinal bars are fabricated from nitinol.

14. The stent of claim 11 wherein the Z-folded or bent longitudinal bars are selectively heated to cause unfolding and result in an increase in longitudinal dimension.

22. The stent of claim 1 further comprising a delivery catheter that winds the stent to a diameter smaller than its expanded diameter.

23. The stent of claim 1 further comprising a delivery catheter that selectively locks and unlocks from the stent.

24. The stent of claim 1 further comprising a delivery catheter that stretches the stent into a generally longitudinal configuration for delivery in the smallest possible profile and with the greatest possible flexibility.

30. The stent of claim 1 further comprising a delivery catheter further comprising a coupler or attachment to the stent that may be selectively uncoupled from the proximal end of the delivery catheter.

31. The stent of claim 30 wherein the coupler holds the stent with a reversible mechanical interference.

32. The stent of claim 30 wherein the coupler holds the stent with a fusible link.

33. The stent of claim 30 wherein the coupler holds the stent with a shape-memory actuator operated mechanical interference.

34. The stent of claim 30 wherein the coupler holds the stent with a friction joint that is overcome by application of hydraulic pressure.

15. A stent, adapted for bridging the neck of an aneurysm, comprising:

an inner helix, and

an outer helix,

wherein the inner and outer helix are separate structures.

16. The stent of claim 15 wherein the inner helix and the outer helix further comprise a plurality of filaments.

17. The stent of claim 15 further comprising a coating to improve radiopacity.

18. The stent of claim 17 wherein the coating is fabricated, at least in part, from tantalum, platinum or gold.

19. The stent of claim 15 wherein the inner helix and the outer helix are counterwound.

20. The stent of claim 15 further comprising a delivery catheter that controllably counterwinds the inner helix and outer helix relative to each other to collapse the stent for delivery to the patient.

21. The stent of claim 15 further comprising a delivery catheter that controllably counterwinds the inner helix and the outer helix relative to each other and stretches the inner helix and the outer helix to compress longitudinally within the delivery catheter.

25. A method of treating cerebrovascular aneurysms comprising the steps of:

accessing the aneurysm with a guide catheter and a guidewire,

delivering a stent to cover the neck of the aneurysm but minimizing coverage of feeder vessels and branch vessels,

delivering embolic material through the openings in the stent to fill and pack the aneurysm, and

adjusting the length of one or more longitudinal bars in the stent through selective heating of the bars.

26. The method of claim 25 further comprising the step of inserting a secondary catheter to selectively heat the longitudinal bars.

27. The method of claim 25 wherein the step of adjusting the length of the longitudinal bars is performed under fluoroscopic guidance.

28. The method of claim 25 wherein the longitudinal bar lengths are adjusted with a catheter that heats the entire stent uniformly.

29. The method of claim 28 further comprising the precursor step of heat-treating only pre-determined bars so that they lengthen upon application of heat.