Apparatus and system for delivery of drug therapies

• US 20040199104A1
• Filed: 04/04/2003
• Published: 10/07/2004
• Est. Priority Date: 04/04/2003
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Ujhelyi, Michael R., Min, Xiaoyi, Mehra, Rahul
• Granted Patent: US 7,186,247 B2
• Time in Patent Office: Days
• US Class Current: 604/65
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/16813 by controlling the degree of opening of the flow line
• CPC Class Codes: A61N 1/0568 with drug delivery

Abstract

A medical delivery system for delivering a fluid to a desired location within a body that includes a first member having an aperture, and a second member adapted to be positioned over the first member. The fluid to be delivered is contained within a fluid storage device, formed by at least one of the first member and the second member. The medical delivery system includes means for repositioning the first member relative to the second member between a first state preventing passage of the fluid through the aperture and a second state enabling passage of the fluid outward from the fluid storage device through the aperture.

Claims

1. A medical delivery system for delivering a fluid to a desired location within a body, comprising:

a first member having an aperture;

a second member adapted to be positioned over the first member;

a first fluid storage device, formed by at least one of the first member and the second member, containing the fluid; and

means for repositioning the first member relative to the second member between a first state preventing passage of the fluid through the aperture and a second state enabling passage of the fluid outward from the first fluid storage device through the aperture.

2. The system of claim 1, further comprising a pressure sensing device communicatively coupled to the repositioning means, the pressure sensing device adapted to sense pressure and generate a pressure feedback signal, wherein the repositioning means repositions the first member relative to the second member in response to the pressure feedback signal.

3. The system of claim 1, wherein the repositioning means delivers a stimulus to the first member to reposition the first member relative to the second member to enable passage of the fluid outward from the first fluid storage device through the aperture.

4. The system of claim 3, wherein the stimulus is one of an electrical stimulus, a magnetic stimulus, and a thermal stimulus.

5. The system of claim 1, wherein the repositioning means delivers a stimulus to the first member and the second member to reposition the first member relative to the second member to enable passage of the fluid outward from the first fluid storage device through the aperture.

6. The system of claim 5, wherein the stimulus is one of an electrical stimulus, a magnetic stimulus, and a thermal stimulus.

7. The system of claim 1, wherein the second member includes a second aperture enabling passage of the fluid outward from the first fluid storage device through the second aperture in the second state, and wherein the first member prevents passage of the fluid through the second aperture and the second member prevents passage of fluid through the aperture of the first member when in the first state.

8. The system of claim 1, wherein the first member is formed from a shape memory alloy.

9. The system of claim 8, wherein the shape memory alloy includes titanium nitinol.

10. The system of claim 3, wherein the first member is adapted to be disposed within the second member.

11. The system of claim 1, further comprising:

a second fluid storage device storing the fluid; and

a fluid transfer device transferring the fluid from the second fluid storage device to the first fluid storage device, wherein the first member and the second member are repositioned from the second state to the first state during transfer of the fluid from the second fluid storage device to the first fluid storage device by the fluid transfer device.

12. A medical delivery system for delivering a fluid to a desired location within a body, comprising:

a first member having an aperture;

a second member adapted to be positioned over the first member;

a first fluid storage device, formed by at least one of the first member and the second member, containing the fluid;

means for repositioning the first member relative to the second member between a first state preventing passage of the fluid through the aperture and a second state enabling passage of the fluid outward from the first fluid storage device through the aperture; and

a pressure sensing device communicatively coupled to the repositioning means, the pressure sensing device adapted to sense pressure and generate a pressure feedback signal, wherein the repositioning means repositions the first member relative to the second member in response to the pressure feedback signal.

13. The system of claim 12, wherein the repositioning means delivers a stimulus to the first member to reposition the first member relative to the second member to enable passage of the fluid outward from the first fluid storage device through the aperture.

14. The system of claim 13, wherein the stimulus is one of an electrical stimulus, a magnetic stimulus, and a thermal stimulus.

15. The system of claim 12, wherein the repositioning means delivers a stimulus to the first member and the second member to reposition the first member relative to the second member to enable passage of the fluid outward from the first fluid storage device through the aperture.

16. The system of claim 15, wherein the stimulus is one of an electrical stimulus, a magnetic stimulus, and a thermal stimulus.

17. The system of claim 12, wherein the second member includes a second aperture enabling passage of the fluid outward from the first fluid storage device through the second aperture in the second state, and wherein the first member prevents passage of the fluid through the second aperture and the second member prevents passage of fluid through the aperture of the first member when in the first state.

18. The system of claim 12, wherein the first member is formed from a shape memory alloy.

19. The system of claim 18, wherein the shape memory alloy includes titanium nitinol.

20. The system of claim 13, wherein the first member is adapted to be disposed within the second member.

21. The system of claim 12, wherein the pressure feedback signal corresponds to maintaining fluid pressure at the aperture at a predetermined flow rate.

22. The system of claim 12, further comprising:

a second fluid storage device storing the fluid; and

a fluid transfer device transferring the fluid from the second fluid storage device to the first fluid storage device, wherein the first member and the second member are repositioned from the second state to the first state during transfer of the fluid from the second fluid storage device to the first fluid storage device by the fluid transfer device.

23. A medical delivery system for delivering a fluid to a desired location within a body, comprising:

a first member having an aperture;

a second member adapted to be positioned over the first member;

a first fluid storage device, formed by at least one of the first member and the second member, containing the fluid;

means for repositioning the first member relative to the second member between a first state preventing passage of the fluid through the aperture and a second state enabling passage of the fluid outward from the first fluid storage device through the aperture;

a pressure sensing device communicatively coupled to the repositioning means, the pressure sensing device adapted to sense pressure and generate a pressure feedback signal, the repositioning means repositioning the first member relative to the second member in response to the pressure feedback signal;

a second fluid storage device storing the fluid; and

a fluid transfer device transferring the fluid from the second fluid storage device to the first fluid storage device, wherein the first member and the second member are repositioned from the second state to the first state during transfer of the fluid from the second fluid storage device to the first fluid storage device by the fluid transfer device, wherein the pressure feedback signal corresponds to maintaining fluid pressure at the aperture at a predetermined flow rate.