Intravascular heat exchange catheter with tissue preservative

• US 20040199114A1
• Filed: 04/01/2003
• Published: 10/07/2004
• Est. Priority Date: 04/01/2003
• Status: Abandoned Application

• Current Assignee: Alsius Corporation
• Original Assignee: Alsius Corporation
• Inventors: Noda, Wayne Arthur
• Application Number:
  US10/404,028
• Publication Number:
  US 20040199114A1
• Time in Patent Office: Days
• US Class Current: 604/113
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities

Abstract

A system and method for treating a patient by inducing therapeutic hypothermia in the patient using an intravascular heat exchange catheter in conjunction with infusing tissue preservative substances into the patient.

Claims

1. A system for treating a patient, comprising:

a heat exchange catheter configured for placement in the patient to induce hypothermia in the patient when coolant is circulated through the catheter;

a heat exchanger supplying coolant to the catheter and receiving coolant from the catheter in a closed circuit; and

at least one source of tissue preservative configured for infusing tissue preservative into the patient.

2. The system of claim 1, wherein the source communicates with the catheter to infuse preservative therethrough into the bloodstream of the patient.

3. The system of claim 1, wherein the patient is a stroke patient, and the preservative includes TPA.

4. The system of claim 1, wherein the patient is a cardiac patient, and the preservative includes at least one substance for preserving heart tissue.

5. The system of claim 4, wherein the substance includes at least one crystalloid.

6. The system of claim 4, wherein the substance includes at least one of:

monosodiumglutamate and a sugar.

7. The system of claim 4, wherein the substance includes at least one of:

Potassium, and Calcium.

8. The system of claim 4, wherein the substance includes a buffer.

9. The substance of claim 8, wherein the substance includes bicarbonate to maintain fluid balance.

10. A method for treating a patient, comprising:

inducing hypothermia in the patient using a closed loop heat exchange catheter; and

infusing at least one tissue preservative into the patient'"'"'s bloodstream.

13. The method of claim 12, wherein the act of infusing is undertaken using the catheter.

14. The method of claim 12, wherein the patient is a stroke patient and the preservative includes TPA.

15. The method of claim 12, wherein the patient is a cardiac patient, and the preservative includes at least one substance selected from the group consisting of:

crystalloids, myocardial preservative substances.

16. A system for treating a patient, comprising:

closed circuit heat exchange means configured for positioning in the patient to exchange heat therewith; and

infusion means for infusing at least one tissue preservative into the patient'"'"'s bloodstream.

17. The system of claim 16, wherein the closed circuit heat exchange means establishes the infusion means.

18. The system of claim 16, wherein the patient is a stroke patient and the preservative includes TPA.

19. The system of claim 16, wherein the patient is a cardiac patient, and the preservative includes at least one substance selected from the group consisting of:

crystalloids, Potassium Chloride (KCl), monosodiumglutamate, buffer substances that prevent cells from exploding, and at least one sugar.