Catheter and method for the delivery of therapeutic agents to tissues
First Claim
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1. A method for delivering a therapeutic implant to a tissue comprising:
- providing an elongate catheter having a distal end including a lumen;
providing a carrier including a therapeutic agent, placing the carrier including the therapeutic agent into the lumen;
advancing the distal end of the catheter to the tissue, and depositing the carrier including the therapeutic agent into the tissue.
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Abstract
A method for delivering a therapeutic implant to a tissue is provided. This method includes providing an elongate catheter having a distal end including a lumen, providing a carrier including a therapeutic agent, placing the carrier including the therapeutic agent into the lumen, advancing the distal end of the catheter to the tissue, and depositing the carrier including the therapeutic agent into the tissue.
67 Citations
16 Claims
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1. A method for delivering a therapeutic implant to a tissue comprising:
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providing an elongate catheter having a distal end including a lumen;
providing a carrier including a therapeutic agent, placing the carrier including the therapeutic agent into the lumen;
advancing the distal end of the catheter to the tissue, and depositing the carrier including the therapeutic agent into the tissue. - View Dependent Claims (2, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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3. The method in accordance with clam 2, wherein the therapeutic agent is selected from the group consisting of VEGF, FGF, PDGF, estrogen, HIF1-α
- , Akt, DEL-1, angiopoietins and combinations thereof
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14. A catheter for placement of an in situ implant, comprising:
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an elongate shaft having a proximal end and a distal end, the shaft defining a first and a second lumen therethrough;
a first sharpened distal tip disposed at the distal end of the shaft, the first distal tip defining a lumen therethrough in fluid communication with the first lumen; and
a second sharpened distal tip disposed at the distal end of the shaft, the second distal tip defining a lumen in fluid communication with the second lumen. - View Dependent Claims (15, 16)
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Specification