Method and apparatus for non-invasively measuring hemodynamic parameters using parametrics
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Accused Products
Abstract
An improved method and apparatus for non-invasively assessing one or more hemodynamic parameters associated with the circulatory system of a living organism. In one aspect, the invention comprises a method of measuring a hemodynamic parameter (e.g., arterial blood pressure) by applanating or compressing portions of tissue proximate to the blood vessel of concern until a desired condition is achieved, and then measuring the hemodynamic parameter. Such applanation effectively mitigates transfer and other losses created by the tissue proximate to the blood vessel, thereby facilitating accurate and robust tonometric measurement. An algorithm adapted to maintain optimal levels of applanation is also described. Methods and apparatus for scaling such hemodynamic parameter measurements based on subject physiology, and providing treatment to the subject based on the measured parameters, are also disclosed.
114 Citations
107 Claims
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1-74. -74. (Cancelled)
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75. A method of measuring the pressure in the blood vessel of a living subject, comprising:
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providing a transducer adapted to generate a signal relating to the pressure applied thereto;
disposing said transducer proximate to said blood vessel;
determining the level of compression where a desired condition of the pressure associated with said blood vessel exists based at least in part on the pressure signal generated by said transducer;
substantially maintaining said level of compression where said desired condition exists;
measuring at least one pressure value using said transducer during at least a portion of said act of substantially maintaining; and
scaling said at least one pressure value based at least in part on a physiologic index of said subject to produce a corrected value, said corrected value being substantially representative of the actual pressure within said blood vessel. - View Dependent Claims (76, 77, 78, 79, 80, 81, 82, 83, 84)
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85. A method of measuring the blood pressure of a living subject, comprising:
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measuring unscaled pressure values from a blood vessel of said subject; and
scaling said unscaled pressure values using a scaling factor, said scaling factor being related to the body mass index (BMI) of said subject.
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86. A method of measuring the blood pressure of a living subject, comprising:
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measuring unscaled pressure values from a blood vessel of said subject; and
scaling said unscaled pressure values using a scaling factor, said scaling factor comprising a physiologic index of said subject, said physiologic index formed by relating at least two physiologic parameters associated with said subject. - View Dependent Claims (87)
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88. A method of measuring the blood pressure of a living subject, comprising:
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measuring unscaled pressure values from a blood vessel of said subject; and
scaling said unscaled pressure values using a scaling factor, said scaling factor being related to the body mass index (BMI) and the pulse pressure (PP) of said subject.
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89. A method of measuring the blood pressure of a living subject, comprising:
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measuring unscaled pressure values from a blood vessel of said subject; and
scaling said unscaled pressure values using a scaling factor, said scaling factor being related to the body mass index (BMI) and the wrist circumference (WC) of said subject.
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90. Apparatus adapted to measure the blood pressure of a living subject, comprising:
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first apparatus adapted to generate a signal relating to the pressure applied thereto; and
second apparatus configured to scale said unscaled pressure values using a scaling factor, said scaling factor being related to the body mass index (BMI) of said subject. - View Dependent Claims (91, 92, 93)
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94. Apparatus adapted to measure the blood pressure of a living subject, comprising:
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first apparatus adapted to generate a signal relating to the pressure applied thereto; and
second apparatus configured to scale said unscaled pressure values using a scaling factor, said scaling factor comprising a physiologic index of said subject, said physiologic index formed by relating at least two physiologic parameters associated with said subject. - View Dependent Claims (95, 96)
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97. Apparatus adapted to measure the blood pressure of a living subject, comprising:
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first apparatus adapted to generate a signal relating to the pressure applied thereto; and
second apparatus configured to scale said unscaled pressure values using a scaling factor, said scaling factor being related to the body mass index (BMI) and the pulse pressure (PP) of said subject.
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98. Apparatus adapted to measure the blood pressure of a living subject, comprising:
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first apparatus adapted to generate a signal relating to the pressure applied thereto; and
second apparatus configured to scale said unscaled pressure values using a scaling factor, said scaling factor being related to the body mass index (BMI) and the wrist circumference (WC) of said subject.
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99. Apparatus adapted to measure the pressure in the blood vessel of a living subject, comprising:
a transducer adapted to generate a signal relating to the pressure applied thereto;
first apparatus adapted to maintain said transducer proximate to said blood vessel; and
second apparatus in operative communication with said transducer and configured to;
determine the level of compression where a desired condition of the pressure associated with said blood vessel exists based at least in part on the pressure signal generated by said transducer;
substantially maintain said level of compression where said desired condition exists;
measure at least one pressure value using said transducer while said desired condition exists; and
scale said at least one pressure value based at least in part on a physiologic index of said subject to produce a scaled value, said scaled value being substantially representative of the actual pressure within said blood vessel. - View Dependent Claims (100, 101, 102)
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103. Apparatus adapted to measure the blood pressure of a living subject, comprising:
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first apparatus adapted to generate a signal relating to the pressure applied thereto, said applied pressure being applied at least in part by tissue interposed between said first apparatus and a blood vessel of said subject;
second apparatus disposed proximate to said first apparatus and adapted to mitigate the effects of said tissue on said applied pressure; and
third apparatus configured to scale said unscaled pressure values using a scaling factor, said scaling factor comprising a physiologic index of said subject, said physiologic index formed by relating at least two physiologic parameters associated with said subject. - View Dependent Claims (104, 105)
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106. A method of measuring the blood pressure of a living subject, comprising:
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a step for measuring unscaled pressure values from a blood vessel of said subject; and
a step for scaling said unscaled pressure values using a scaling factor, said scaling factor comprising a physiologic index of said subject, said physiologic index formed by performing a step for relating at least two physiologic parameters associated with said subject.
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107. Apparatus adapted to measure the blood pressure of a living subject, comprising:
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means for generating a signal relating to the pressure applied thereto; and
means for scaling said unscaled pressure values using a scaling factor, said scaling factor comprising a physiologic index of said subject, said physiologic index formed by relating at least two physiologic parameters associated with said subject.
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Specification