Dielectrophoresis device and method having non-uniform arrays for manipulating particles
First Claim
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1. A device for manipulating particles using dielectrophoresis, the device comprising:
- a substrate across which the particles move;
a non-uniform array of insulating features on the substrate; and
a plurality of electrodes positioned to generate a spatially non-uniform electric field across the non-uniform array.
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Abstract
Microfluidic devices according to embodiments of the present invention include an inlet port, an outlet port, and a channel or chamber having a non-uniform array of insulating features on one or more surfaces. Electrodes are provided for generation of a spatially non-uniform electric field across the array. A voltage source, which may be an A.C. and/or a D.C. voltage source may be coupled to the electrodes for the generation of the electric field.
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18 Claims
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1. A device for manipulating particles using dielectrophoresis, the device comprising:
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a substrate across which the particles move;
a non-uniform array of insulating features on the substrate; and
a plurality of electrodes positioned to generate a spatially non-uniform electric field across the non-uniform array. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method for manipulating particles using dielectrophoresis, the method comprising:
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generating a spatially non-uniform electric field;
passing a sample fluid containing the particles across the non-uniform array, the spatially non-uniform electric field exerting a dielectrophoretic force on the particles thereby constraining motion of at least one particle; and
trapping at least one particle at a location in the non-uniform array, wherein the location is determined at least in part based on electric and geometrical properties of the particle. - View Dependent Claims (15, 16, 17, 18)
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Specification