Cell interaction culture system and uses thereof
First Claim
1. A cell co-culture system comprising a cell culture container partitioned into two or more compartments by one or more removable partition units, wherein the bottom edge of said removable partition unit(s) is in contact with the cell culture surface of said cell culture container, wherein different types of cells can be cultured in each of said compartments, and cellular interaction or cell migration is to be observed in an area on said cell culture container covered by the bottom edge(s) of said removable partition unit(s) after removal of said partition unit(s).
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Abstract
The present invention relates to a novel cell co-culture system and methods of using the same for studying cellular interactions. The co-culture system comprises a cell culture container partitioned into multiple compartments by removable partition units/separating walls. Different cell types or materials can be placed and cultured in the various compartments. When the cells are ready for cell interaction studies, the removable walls separating two adjacent compartments are removed and cellular interaction can then be studied in a defined area, i.e. the area previously occupied by the bottom edges of the removable walls. The present invention thus provides a cell co-culture system that would set up a new and flexible platform for most cell interaction studies.
45 Citations
34 Claims
- 1. A cell co-culture system comprising a cell culture container partitioned into two or more compartments by one or more removable partition units, wherein the bottom edge of said removable partition unit(s) is in contact with the cell culture surface of said cell culture container, wherein different types of cells can be cultured in each of said compartments, and cellular interaction or cell migration is to be observed in an area on said cell culture container covered by the bottom edge(s) of said removable partition unit(s) after removal of said partition unit(s).
Specification