Method for detection and display of extravasation and infiltration of fluids and substances in subdermal or intradermal tissue

• US 20040215081A1
• Filed: 04/23/2003
• Published: 10/28/2004
• Est. Priority Date: 04/23/2003
• Status: Abandoned Application

• Current Assignee: United States Of America As Represented By The Secretary Of The Air Force
• Original Assignee: United States Of America As Represented By The Secretary Of The Air Force
• Inventors: Callard, David M., Crane, Robert L.
• Application Number:
  US10/421,270
• Publication Number:
  US 20040215081A1
• Time in Patent Office: Days
• US Class Current: 600/473
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/02042 Determining blood loss or bleeding, e.g. during a surgical procedure
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 5/16836 by sensing tissue properties at the infusion site, e.g. for detecting infiltration detecting tissue temperature for diagnostic purposes A61M39/0247

Abstract

A method for the real-time visualization and detection of extravasated and or infiltrated fluid and substances, including blood, that occur near the cannulation site of an injection is described wherein illumination or transillumination with near infrared light is used to image the contrast in real-time between absorbing and nonabsorbing subdermal and intradermal structures of blood vessels and remaining surrouding tissue, foreign substances and other structures in order to establish a baseline image of the body area of interest, and any new image is monitored and compared with the baseline image to detect the extravasation and/or infiltration of fluids and substances, including blood, around a vein or artery into the subdermal or intradermal tissue.

Claims

1. A method for real-time visualization and detection of extravasted and/or infiltrated fluids and substances, including blood, that occur near the cannulation site of an injection comprising the steps of:

(a) providing a light source in the wavelength range of about 0.3 to about 1.0 micron;

(b) illuminating a portion of the body near the intended site of an injection in at least one of a reflection mode and a transillumination mode;

(c) providing a detector sensitive to light in said wavelength range of said light source for receiving said light transmitted from said portion of the body;

(d) selectively filtering the light received by said detector using a filter having a narrow passband centered substantially on at least one wavelength in said wavelength range of said light source;

(e) generating a first image from the filtered light to provide a baseline image of the subdermal and intradermal tissues in said portion of the body;

(f) generating at least one additional image of said portion of the body during a procedure that includes an injection at said body portion; and

(g) comparing said at least one additional image with said baseline image to detect changes near the vasculature in said portion of the body to detect extravasation or infiltration in said portion of the body.

2. The method of claim 1 wherein said detector includes an image intensifier tube, photomultiplier tube, a photo diode, a charge coupled device, or a CMOS.

3. The method of claim 1 wherein said step of filtering said detected energy is performed using a filter having a narrow passband centered substantially on at least one wavelength selected from the group consisting of 0.32, 0.345, 0.41, 0.43, 0.455, 0.54, 0.56, 0.58, 0.7, 0.76 micron.

4. A method for monitoring a medical procedure that includes an injection procedure at a portion of the body, comprising the steps of:

(a) providing a light source in the wavelength range of about 0.3 to about 1.0 micron;

(b) illuminating a portion of the body near the intended site of an injection in at least one of a reflection mode and a transillumination mode;

(c) providing a detector sensitive to light in said wavelength range of said light source for receiving said light transmitted from said portion of the body;

(d) selectively filtering the light received by said detector using a filter having a narrow passband centered substantially on at least one wavelength in said wavelength range of said light source;

(e) generating a series of images from the filtered light of the subdermal and intradermal tissues in said portion of the body during the medical procedure; and

(f) comparing said images to observe changes near the vasculature in said portion of the body and to detect extravasation and/or infiltration in said portion of the body.

5. The method of claim 4 wherein said detector includes an image intensifier tube, photomultiplier tube, a photo diode, a charge coupled device, or a CMOS.

6. The method of claim 4 wherein said step of filtering said detected energy is performed using a filter having a narrow passband centered substantially on at least one wavelength selected from the group consisting of 0.32, 0.345, 0.41, 0.43, 0.455, 0.54, 0.56, 0.58, 0.7, 0.76 micron.