System for anesthetizing laboratory animals

• US 20040216737A1
• Filed: 06/03/2004
• Published: 11/04/2004
• Est. Priority Date: 07/26/2001
• Status: Abandoned Application

• Current Assignee: Euthanex Corporation
• Original Assignee: Euthanex Corporation
• Inventors: Agelan, Alexis, Eldon, James, Anderson, Leslie B.
• Application Number:
  US10/860,230
• Publication Number:
  US 20040216737A1
• Time in Patent Office: Days
• US Class Current: 128/203.12
• CPC Class Codes: A01K 1/031 Cages for laboratory animals; Cages for measuring metabolism of animals
• CPC Class Codes: A61D 7/04 Devices for anaesthetising animals by gases or vapours; Inhaling devices
• CPC Class Codes: A61M 16/0093 by adsorption, absorption or filtration
• CPC Class Codes: A61M 16/1015 using a gas flush valve, e.g. oxygen flush valve
• CPC Class Codes: A61M 16/104 specially adapted for anaesthetics A61M16/18 takes precedence
• CPC Class Codes: A61M 16/1065 in the expiratory path
• CPC Class Codes: A61M 16/18 Vaporising devices for anaesthetic preparations
• CPC Class Codes: A61M 2205/84 for treating several patients simultaneously

Abstract

A method and apparatus for anesthetizing one or more laboratory animals is provided. An anesthetic component is introduced into a pressurized gas stream for delivery to laboratory animals. In one embodiment of the invention, a solo apparatus is used to administer anesthetic component to a single animal. The apparatus may also include a group apparatus connected to the pressurized gas stream that administers anesthesia to one or more animals simultaneously. One or more solo and/or group apparatuses may be used to administer anesthetic components to different animals at various dosages. The apparatuses of the present invention include a non-rebreathing feature that uses a vacuum-sensitive check valve. The valve permits the delivery of anesthetic gas to the animal only when the animal inhales. The present invention may also include a thermoregulatory system that transfers heat to animals as they receive anesthesia, and an exhaust system to capture exhaust gases.

Claims

1. An anesthesia system for administering an anesthetic gas to the nose of an animal, said anesthesia system comprising:

A. a mask having a receptacle adapted to surround and form a fluid path to the animal'"'"'s nose;

B. a breather enclosure forming an air exchange chamber, said breather enclosure comprising a connector configured for coupling with said mask to connect the receptacle and air exchange chamber in fluid communication;

C. an inlet hub extending inside said air exchange chamber and forming an inlet port through a wall in the breather enclosure, said inlet port being adapted to convey the anesthetic gas into the chamber and to the mask; and

D. a check valve connected with the inlet hub and extending within said air exchange chamber, said check valve being operable in response to relative pressure in the air exchange chamber between an open position, which permits anesthetic gas to enter the air exchange chamber, and a closed position, which substantially prevents anesthetic gas from entering the air exchange chamber,

wherein, the check valve moves to the open position in response to vacuum pressure created when the animal inhales, said check valve being normally biased in the closed position.

2. The anesthesia system of claim 1 comprising a cone-shaped receptacle on the mask, said cone-shaped receptacle adapted to receive and conform with the contour of the animal'"'"'s nose to minimize void space between the animal'"'"'s nose and the mask.

3. The anesthesia system of claim 1, wherein the mask comprises a resilient flexible material adapted to deflect and conform to the contour of the animal'"'"'s nose.

4. The anesthesia system of claim 1, wherein the breather enclosure comprises a connector and the mask comprises a connecter end configured to detachably couple the mask with the connector on the breather enclosure.

5. The anesthesia system of claim 4, comprising an intubating tube having a tube end configured for detachable coupling with the connector on the breather enclosure to enable substitution of the mask with said intubating tube.

6. The anesthesia system of claim 1, wherein the volume of the air exchange chamber is approximately between 1.0-4.0 cubic centimeters.

7. A self-regulating on-demand breathing apparatus for administering an anesthetic gas to the nose of an animal, said breathing apparatus comprising:

A. an enclosure forming a chamber and comprising an inlet hub extending within said chamber, said inlet hub forming an inlet port through a wall of the enclosure adapted to convey the anesthetic gas through the wall into the chamber;

B. a receptacle extending from the enclosure and forming a fluid path between the animal'"'"'s nose and the chamber; and

C. a check valve connected with the inlet hub and extending within said chamber adjacent the receptacle, said check valve being operable in response to relative pressure in the chamber between an open position, which permits anesthetic gas to enter the chamber, and a closed position, which substantially prevents anesthetic gas from entering the chamber,

wherein the check valve moves to the open position in response to vacuum pressure created when the animal inhales to administer the anesthetic gas in response to the animal'"'"'s breathing, said check valve being normally biased in the closed position.

8. The self-regulating breathing apparatus of claim 7, wherein the receptacle comprises a first cone-shaped mask adapted to receive and conform with the contour of the animal'"'"'s nose to minimize void space between the first animal'"'"'s nose and the mask.

9. The self-regulating breathing apparatus of claim 8, wherein the enclosure comprises a connector and the first mask has an end configured to detachably couple the first mask with the connector on the enclosure.

10. The self-regulating breathing apparatus of claim 9, comprising an intubating tube having a tube end configured for detachable coupling with the connector on the enclosure to enable substitution of the mask with said intubating tube.

11. The self-regulating breathing apparatus of claim 9, comprising a second mask configured for detachable coupling with the connector on the enclosure to enable substitution of the first mask with the second mask.

12. The self-regulating breathing apparatus of claim 11, wherein the first mask is configured to conform to the anatomy of a first species of animal, and the second mask is configured to conform to the anatomy of a second species of animal.

13. The self-regulating breathing apparatus of claim 7, wherein the receptacle comprises a base portion extending from the enclosure and a head restraint portion detachably coupled with the base portion.

14. The self-regulating breathing apparatus of claim 13 comprising a first saddle portion on the base portion and a second saddle portion on the head restraint portion, said second saddle portion being configured for complementary alignment with said first saddle portion to form an elliptical nose aperture.

15. The self-regulating breathing apparatus of claim 13, wherein the enclosure comprises a centrally located barrier, said enclosure forming an inhalation chamber and an exhaust chamber separated from the inhalation chamber by said barrier, said inlet hub and check valve extending within said inhalation chamber.

16. The self-regulating breathing apparatus of claim 7 comprising a radiolucent material.

17. The self-regulating breathing apparatus of claim 7, wherein the volume of the chamber is approximately between 1.0-4.0 cubic centimeters.

18. A breathing apparatus for administering an anesthetic gas to the nose of an animal, said breathing apparatus comprising:

A. an enclosure having a hollow interior and a barrier extending through the hollow interior to form an inhalation chamber and an exhaust chamber;

B. a first sidewall on the enclosure forming an inlet port that extends through the first sidewall in fluid communication with the inhalation chamber;

C. a second sidewall on the enclosure forming an exhaust port that extends through the second sidewall in fluid communication with the exhaust chamber;

D. a receptacle extending from the enclosure and forming a fluid path between the animal'"'"'s nose and the inhalation chamber; and

E. a check valve extending from the inlet port and projecting into the inhalation chamber adjacent the receptacle, said check valve being operable in response to vacuum pressure created in said inhalation chamber when the animal inhales,

wherein the check valve is configured to move to an open position in response to vacuum pressure created in the inhalation chamber when the animal inhales to permit anesthetic gas to enter the inhalation chamber, and to a closed position, in which the check valve prevents the entry of anesthetic gas into the inhalation chamber, said check valve being normally biased in the closed position.

19. The breathing apparatus of claim 18, wherein the receptacle comprises a base portion and a head restraint portion configured to connect with the base portion around the animal'"'"'s head.

20. The breathing apparatus of claim 19, wherein the base comprises a pair of longitudinal grooves and the head restraint comprises a pair of flanges configured to slidably engage said grooves to detachably connect the head restraint with said base.

21. The breathing apparatus of claim 19 comprising a restraint lock screw extending through the head restraint and configured to frictionally engage the base when the head restraint is connected with the base to secure the head restraint in a fixed position relative to the base.

22. The breathing apparatus of claim 19 comprising a first saddle portion on the base portion and a second saddle portion on the head restraint portion, said second saddle portion being configured for complementary alignment with said first saddle portion to form an elliptical nose aperture.

23. The breathing apparatus of claim 19, wherein the enclosure forms a funnel-shaped conduit having a wide conduit end adjacent to the receptacle, and a narrow conduit end connected with the inhalation chamber.

24. The breathing apparatus of claim 23, wherein the narrow conduit end is adapted to receive the anterior end of the animal'"'"'s nose and permit said anterior end to project out of the conduit into the inhalation chamber.

25. The breathing apparatus of claim 18, wherein the barrier forms a notch to connect the conduit and the exhaust chamber in fluid communication.

26. The breathing apparatus of claim 18, wherein the first sidewall is the same as the second sidewall.

27. An anesthesia system for administering an anesthetic gas to a plurality of animals comprising:

A. a source of a pressurized gas operable to produce a flow of pressurized gas;

B. a vaporizer fluidly connected to said source of pressurized gas and adapted to introduce an anesthetic component into the flow of pressurized gas to create an anesthetic gas mixture;

C. a manifold fluidly connected to said vaporizer to receive said anesthetic gas mixture, said manifold comprising a first outlet port and a second outlet port, said first and second outlet ports being operable to deliver the gas mixture through said ports simultaneously;

D. a first conduit connected with the first outlet port, and a second conduit connected with the second outlet port;

E. a group apparatus connected with the first conduit for administering the anesthetic gas to a first group of animals;

F. a plurality of solo apparatuses connected with said second conduit in a parallel arrangement to deliver the gas mixture to a second group of animals, each of said solo apparatuses comprising a breather adapted for connection with up to one of said second group of animals; and

G. a flow regulator connected in the first conduit between said manifold and said group apparatus, said flow regulator comprising a throttling mechanism operable to decrease the flow of gas into the group apparatus and build a back pressure of gas in the manifold, said second conduit being configured to evenly distribute said back pressure to the solo apparatuses such that each solo apparatus is supplied with an equal gas pressure.