Cosmetic and Pharmaceutical Masks Based on Ion-Pair Delivery System

• US 20040219124A1
• Filed: 05/01/2003
• Published: 11/04/2004
• Est. Priority Date: 05/01/2003
• Status: Abandoned Application

• Current Assignee: Shyam K. Gupta
• Original Assignee: Shyam K. Gupta
• Inventors: Gupta, Shyam K.
• Application Number:
  US10/249,701
• Publication Number:
  US 20040219124A1
• Time in Patent Office: Days
• US Class Current: 424/70.13
• CPC Class Codes: A61K 2800/242 Exothermic; Self-heating; Heating sensation
• CPC Class Codes: A61K 8/0212 Face masks
• CPC Class Codes: A61K 8/733 Alginic acid; Salts thereof
• CPC Class Codes: A61K 8/9711 Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
• CPC Class Codes: A61K 8/9717 Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
• CPC Class Codes: A61K 8/9722 Chlorophycota or Chlorophyta [green algae], e.g. Chlorella
• CPC Class Codes: A61K 8/9767 Pinaceae [Pine family], e.g. pine or cedar
• CPC Class Codes: A61K 8/9789 Magnoliopsida [dicotyledons]
• CPC Class Codes: A61K 8/9794 Liliopsida [monocotyledons]
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/02 for chemically bleaching or whitening the skin
• CPC Class Codes: A61Q 19/06 for countering cellulitis
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations

Abstract

The present invention discloses a novel ion-pair delivery system based mask compositions for face, hair, skin, and body applications. These compositions come off from the site of their application essentially in one piece with the appearance, for example, of a piece of sea-weed or a continuous film. These mask compositions are suitable for a variety of delivery system methods, such as peel-off mask, moisturizing mask, exfoliating mask, prosthetic mask, soaking mask, depilatory mask, rub-off mask, two-phase mask, two-compartment mask, heat-releasing mask, and such. These mask compositions are made from the biopolymer based films that are cross-linked with divalent or trivalent metal cations. During the cross-linking process, such divalent and trivalent metal cations may also act as release agents for other face, hair, skin, and body beneficial compositions in their enhanced bioavailable forms by an ion-pair activation mechanism.

Claims

1. A cosmetic or pharmaceutical mask composition suitable for facial, hair, skin, or body application comprising:

(i) At least one biopolymer, polymer, or polyvalent metal complexing composition as one component of the ion-pair, which forms the matrix of mask composition (Part I), from about 0.1% to about 50%, and

(ii) At least one divalent or trivalent metal cation as the other component of the ion-pair (Part II), which causes the cross-linking of the first component of the ion-pair composition (Part I), from about 0.1% to about 50%, and

(iii) At least one skin, hair, or body beneficial cosmetic or pharmaceutical composition, from about 0.0001% to about 25%, and

(iv) A cosmetically or pharmaceutically acceptable delivery system or a carrier base composition.

2. A composition according to claim 1, wherein biopolymer or polymer can be additionally selected from algin, alginic acid, sodium alginate, potassium alginate, ammonium alginate, TEA alginate, amine salts of alginic acid, amino acid salts of alginic acid, derivatives of alginic acid, gellan gum, xanthan gum, polyacrylic acid, sodium polyacrylate, potassium polyacrylate, ammonium polyacrylate, TEA polyacrylate, derivatives of polyacrylic acid, chitosan, psyllium husk, agar, carrageenan, gelatin, pectin, locust bean gum, gum arabica, and combinations thereof.

3. A composition according to claim 1, wherein ion-pair forming cross-linking composition can be additionally selected from various organic and inorganic salts and derivatives of divalent and trivalent metals, such as calcium chloride, calcium sulfate, Epsom salt, Dead Sea salt, calcium nitrate, calcium gluconate, calcium ascorbate, calcium lactobionate, calcium citrate, calcium carbonate, calcium salicylate, calcium hydroxycitrate, zinc chloride, zinc gluconate, magnesium chloride, magnesium sulfate, magnesium carbonate, magnesium ascorbate, magnesium citrate, magnesium salicylate, aluminum chloride, aluminum hydroxide, boric acid, borax and such, and the combinations thereof.

4. A composition according to claim 1, wherein skin beneficial cosmetic or drug composition can be additionally selected to provide treatment of skin aging, skin wrinkles reduction, skin exfoliating, treatment of acne, treatment of rosacea, age-spots reduction, skin surface whitening, skin surface brightening, striae distensae (stretch marks) reduction, treatment of pimples, treatment of skin infections and lesions, varicose and spider veins reduction, blood microcirculation improvement, UVA/UVB protection of skin, skin redness reduction benefits, antimicrobial agents, antifungal agents, Vitamins and provitamins, hormones, peptides, skin protectants, excess topical fat reduction, cellulite control, skin and body toning benefits, or combinations thereof.

5. A composition according to claim 1, wherein skin beneficial cosmetic or drug composition can be additionally selected from various sea-weed parts and their extracts that includes Algae extract, Spirulina, Fucoidan, Laminaria, Corollina, Codium, Ulva lactata, Plankton, Hypnea, Rhodophycea, Ceramium, Fucus, Enteromorpha, Chondrus, Maris, Macrocystis, Gelidium, Pelvetia, Crithmum, Sea Fennel, Undaria, Ascophyllum, Alaria, Palmaria, Porphyra, Sargassum, Eisenia, Monostroma, Phaeodactylum, Chrolella, and the plants from hydrothermal vents that includes Thermus, Alteromonas, Anacystis, and such.

6. The compositions according to claim 1, wherein the cosmetically or pharmaceutically acceptable delivery system can be traditional water and oil emulsions, suspensions, colloids, microemulsions, clear solutions, suspensions of nanoparticles, emulsions of nanoparticles, or anhydrous compositions.

7. A composition according to claim 1, wherein the mask may be a two-compartment composition. The composition in the first compartment can be anhydrous pr water-based. The composition in the second compartment can similarly be anhydrous or water-based.

8. A composition according to claim 1, wherein cosmetically or pharmaceutically acceptable delivery system or carrier base can optionally include additional skin beneficial ingredients selected from skin cleansers, surfactants (cationic, anionic, non-ionic, amphoteric, and zwitterionic), skin and hair conditioning agents, vitamins, hormones, minerals, plant extracts, anti-inflammatory agents, concentrates of plant extracts, emollients, moisturizers, skin protectants, humectants, silicones, skin soothing ingredients, analgesics, skin penetration enhancers, solubilizers, moisturizers, emollients, anesthetics, colorants, perfumes, preservatives, seeds, broken seed nut shells, silica, clays, beads, luffa particles, polyethylene balls, mica, pH adjusters, processing aids, and combinations thereof. The quantities of such ingredients can be safe and effective amounts as needed, and not limited to any specific limits.

9. A composition according to claim 4, wherein the composition to promote excess fat reduction, cellulite control, or toning benefits can be selected from the group consisting of Forskohlin extract (from Coleus forskohlii plant), Hydroxycitric acid, (from Garcinia cambogia, and plants of Garcinia family), L-Carnitine, Creatine, Human growth hormone (HGH), Chromium picolinate, Kola seed extract, Caffeine, Niacinamide, Psyllium husk, Chitosan, Lipoprotein complexes, Polyphenols, Gymnemic acid, Pyruvic acid and Pyruvate salts, salts of Hydroxycitric acid, Phaseolamin (from Phaseolus vulgaris extract), DHEA, Chitosan, Theophylline, Theobromine (or salts thereof such as Aminophylline), Roselle tea extract, Arabinose, Inosine, Adenosine, Fructose-1,6-diphosphate, Adenosine triphosphate (ATP), Adenosine diphosphate (ADP), Indomethacin, Baicalein, Extract of the plant of genus Tephrosia, Natriuretic peptide, Laminaria extract, Extract from berries of Panax genus plant, Gymnema sylvestre extract, 9-cis, 11-trans Conjugated linoleic acid and 10-trans, 12-cis conjugated linoleic acid isomers (conjugated linoleic acid, CLA), Synephrine, Hordenine, Octopamine, Tyramine, N-Methyltyramine, Azaftig, Extract of Climbing ivy (Hedera helix), Extract of Arnica (Arnica montana), Extract of Rosemary (Rosmarinus officinalis), Extract of Marigold (Calendula officinalis), Extract of Sage (Salvia officinalis), Extract of Ginseng (Panax ginseng), Extract of St. Johns-wart (Hypericum perforatum), Extract of Ruscus (Ruscus aculeatus), Extract of meadowsweet (Filipendula ulmaria), Extract of Orthosiphon (Ortosifon stamincus), and combinations thereof.

10. A composition according to claim 4, wherein the cosmetic or drug ingredient that can be selected from a group consisting of antioxidants, collagen and elastin synthesis boosters, various hydroxy acids (alpha hydroxy acids, beta hydroxy acids, and polyhydroxy acids), vitamins, hormones, skin whitening agents, UVA/UVB sunscreens, antimicrobial agents, antifungal agents, blood microcirculation improvement agents (vasodilatory or vasoconstrictive), skin protectant drug actives, and combinations thereof. The quantities of such compositions can be safe and effective amounts as needed, and not limited to any specific limits.

11. A composition according to claim 4, wherein the composition to promote collagen and elastin in the skin can be selected from Ascorbic acid, Ascorbic acid derivatives, Glucosamine ascorbate, Arginine ascorbate, Lysine ascorbate, Glutathione ascorbate, Nicotinamide ascorbate, Niacin ascorbate, Allantoin ascorbate, Creatine ascorbate, Creatinine ascorbate, Chondroitin ascorbate, Chitosan ascorbate, DNA Ascorbate, Carnosine ascorbate, Vitamin E, various Vitamin E derivatives, Tocotrienol, Rutin, Quercetin, Hesperedin (Citrus sinensis), Diosmin (Citrus sinensis), Mangiferin (Mangifera indica), Mangostin (Garcinia mangostana), Cyanidin (Vaccinium myrtillus), Astaxanthin (Haematococcus algae), Lutein (Tagetes patula), Lycopene (Lycopersicum esculentum), Resveratrol (Polygonum cuspidatum), Tetrahydrocurcumin (Curcuma longa), Rosmarinic acid (Rosmarinus officinalis), Hypericin (Hypericum perforatum), Ellagic acid (Punica granatum), Chlorogenic acid (Vaccinium vulgaris), Oleuropein (Olea europaea), Î

±

-Lipoic acid, Niacinamide lipoate, Glutathione, Andrographolide (Andrographis paniculata), Carnosine, Niacinamide, Potentilla erecta extract, Polyphenols, Grapeseed extract, Pycnogenol (Pine Bark extract), and combinations thereof. The quantities of such compositions can be safe and effective amounts as needed, and not limited to any specific limits.

12. A composition according to claim 4, wherein the skin beneficial hydroxy acid can be selected from the group consisting of salicylic acid, lactic acid, glycolic acid, malic acid, mandelic acid, ascorbic acid, ascorbyl phosphoric acid, hydroxycitric acid, hydroxytetronic acid, citric acid, aleuritic acid, ellagic acid, rosmarinic acid, chlorogenic acid, polysulfonic acid, and hyaluronic acid (HYA). The quantities of such compositions can be safe and effective amounts as needed, and not limited to any specific limits.

13. A composition according to claim 4, wherein the skin beneficial skin whitening agent can be selected from hydroquinone, arbutin, hydroquinone derivatives, Paper Mulberry extract (Broussonetia kazinoke), Mitracarpe extract (Mitracarpus scaber), Bearberry extract (Arctostaphylos uva ursi), Yellow Dock extract (Rumex crispus and Rumex occidentalis), Glutathione, Leucocyte extract, Aspergillus orizae extract (Aspergillus orizae), Licorice Root extract (Glycyrrhiza glabra), Rosmarinic acid (Rosmarinus officinalis), Tetrahydrocurcumin, Green Tea extract (Camellia sinensis), Yohimbe extract (Pausinystalia yohimbe), Ecklonia cava extract, niacinamide, Hydroxytetronic acid, Spondias mombin extract, Maprounea guianensis extract, Walteria indica extract, Gouania blanchetiana extract, Cordia schomburgkii extract, Randia armata extract, Hibiscus furcellatus extract, and combinations thereof. The quantities of such compositions can be safe and effective amounts as needed, and not limited to any specific limits.

14. A composition according to claim 4, wherein the skin beneficial antioxidant composition can be selected from Ascorbic acid, Ascorbic acid derivatives, Vitamin E, Vitamin E derivatives, Tocotrienol, Rutin, Quercetin, Hesperedin (Citrus sinensis), Diosmin (Citrus sinensis), Mangiferin (Mangifera indica), Mangostin (Garcinia mangostana), Cyanidin (Vaccinium myrtillus), Astaxanthin (Haematococcus algae), Lutein (Tagetes patula), Lycopene (Lycopersicum esculentum), Resveratrol (Polygonum cuspidatum), Tetrahydrocurcumin (Curcuma longa), Rosmarinic acid (Rosmarinus officinalis), Hypericin (Hypericum perforatum), Ellagic acid (Punica granatum), Chlorogenic acid (Vaccinium vulgaris), Oleuropein (Olea europaea), alpha-Lipoic acid, Glutathione, Andrographolide, Grapeseed extract, Green Tea Extract, Polyphenols, Pycnogenol (Pine Bark extract), White Tea extract, Black Tea extract, (Andrographis paniculata), Carnosine, Niacinamide, Emblica extract, and combinations thereof. The quantities of such compositions can be safe and effective amounts as needed, and not limited to any specific limits.

15. A composition according to claim 4, wherein the UVA/UVB sunscreen composition can be selected from Titanium dioxide, Zinc oxide, Galanga extract (Kaempferia galanga), Benzophenone-3, Benzophenone-4, Ethylhexyl Methoxycinnamate, Homosalate, Ethylhexyl salicylate, Octocrylene, Menthyl anthranilate, Avobenzone, Lawsone, Sulisobenzone, Trolamine salicylate, Lawsone, Glyceryl aminobenzoate, Cinoxate, and PABA. and combinations thereof. The quantities of such compositions can be safe and effective amounts as needed, and not limited to any specific limits.

16. A Composition According to claim 4, wherein the blood microcirculation improvement composition can be selected from Horse Chestnut Extract (Aesculus hippocastanum extract)), Esculin, Escin, Yohimbine, Capsicum Oleoresin, Capsaicin, Niacin, Niacin Esters, Methyl Nicotinate, Benzyl Nicotinate, Ruscogenins (Butchers Broom extract;

Ruscus aculeatus extract), Diosgenin (Trigonella foenumgraecum, Fenugreek), Emblica extract (Phyllanthus emblica extract), Asiaticoside (Centella asiatica extract), Boswellia Extract (Boswellia serrata), Ginger Root Extract (Zingiber Officianalis), Piperine, Vitamin K, Melilot (Melilotus officinalis extract), Glycyrrhetinic acid, Ursolic acid, Sericoside (Terminalia sericea extract), Darutoside (Siegesbeckia orientalis extract), Amni visnaga extract, extract of Red Vine (Vitis-Vinifera) leaves, apigenin, phytosan, luteolin, and combinations thereof. The quantities of such compositions can be safe and effective amounts as needed, and not limited to any specific limits.

17. A composition according to claim 4, wherein the antimicrobial composition can be selected from Berberine, Triclosan, Triclocarban, various Tritons (quaternary ammonium compounds), Benzyl Alcohol, Dehydroacetic Acid, Phenoxyethanol, and combinations thereof. The quantities of such compositions can be safe and effective amounts as needed, and not limited to any specific limits.

18. A composition according to claim 4, wherein the vitamin composition can be selected from Vitamin A, members of Vitamins B group, Vitamin C, Vitamin D, Vitamin E, Vitamin K, Carotenes, Biotin, Folic Acid, and combinations thereof. The quantities of such ingredients can be safe and effective amounts as needed, and not limited to any specific limits.

19. A composition according to claim 4, wherein the hormone composition can be selected from progesterone, androsterone, dehydroepiandrosterone (DHEA), Pregnenolone, androstenedione, melatonin, testosterone, and combinations thereof. The quantities of such compositions can be safe and effective amounts as needed, and not limited to any specific limits.

20. A composition according to claim 4, wherein the skin protectant drug composition can be selected from Allantoin, petrolatum, glycerin, dimethicone, urea, calamine, cocoa butter, kaolin, zinc acetate, zinc carbonate, and combinations thereof. The quantities of such compositions can be safe and effective amounts as needed, and not limited to any specific limits.