Methods for monitoring treatment of disease

• US 20040221855A1
• Filed: 10/17/2003
• Published: 11/11/2004
• Est. Priority Date: 10/17/2002
• Status: Abandoned Application

• Current Assignee: Control Delivery Systems Inc. (EyePoint Pharmaceuticals, Inc.)
• Original Assignee: Control Delivery Systems Inc. (EyePoint Pharmaceuticals, Inc.)
• Inventors: Ashton, Paul
• Application Number:
  US10/688,151
• Publication Number:
  US 20040221855A1
• Time in Patent Office: Days
• US Class Current: 128/898
• CPC Class Codes: G01N 2800/16 Ophthalmology
• CPC Class Codes: G01N 2800/52 Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
• CPC Class Codes: G16H 10/20 for electronic clinical trials or questionnaires
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients

Abstract

The invention provides statistical methods for identifying measurements that can be used to generate variables that are associated with clinical outcomes of treatment regimens for disease. The invention also provides methods for using such measurements to monitor the effectiveness of an ongoing disease treatment regimen, databases which contain information about measurements and variables and their relationships to clinical outcomes, and pharmaceutical products which incorporate instructions on the use of the methods and databases of the invention. The invention provides a specific application of these methods and products to the treatment of ocular diseases, particularly macular edema, in particular for the treatment of macular edema with implantable devices and compositions that provide sustained release of corticosteroids.

Claims