Transdermal assay with magnetic clamp
First Claim
1. A transdermal assay apparatus, comprising:
- a) a first lower member having a sample surface configured to receive an array of samples and having an array of samples provided on said sample surface;
b) a tissue specimen that overlays said array of samples;
c) a second upper member having an array of reservoirs each having an opening on the surface of said second member, wherein said sample surface array and said reservoir array are substantially aligned with one another when in use;
wherein said array of samples provided on said first member has an active component that transfers across said tissue specimen into said array of reservoirs of said second member.
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Accused Products
Abstract
The transdermal assay apparatus includes first, second, and third members. The first member has one or more sample surfaces, each of which is configured to receive a sample thereon. The second member defines one or more reservoirs, each of which has an opening on a surface of the second member. Each sample surface is substantially the same size as each opening. The transdermal assay apparatus also includes a magnetic clamp configured to clamp a tissue specimen between the sample surface and the opening. The magnetic clamp preferably includes a magnet having a strength that is selected based on the clamping force required between the first member and the second member. The invention also provides a method for using a transdermal assay apparatus.
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Citations
41 Claims
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1. A transdermal assay apparatus, comprising:
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a) a first lower member having a sample surface configured to receive an array of samples and having an array of samples provided on said sample surface;
b) a tissue specimen that overlays said array of samples;
c) a second upper member having an array of reservoirs each having an opening on the surface of said second member, wherein said sample surface array and said reservoir array are substantially aligned with one another when in use;
wherein said array of samples provided on said first member has an active component that transfers across said tissue specimen into said array of reservoirs of said second member. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41)
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Specification