Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof
First Claim
1. A gastro-electric stimulation system for at least one of reducing the pH of gastric acid in a stomach of a patient and reducing an amount of gastric acid produced in the stomach of the patient, comprising:
- a INS for producing at least one electrical stimulation signal;
at least one medical electrical lead having a proximal end and a distal end, the proximal end being connected to the INS, the distal end being adapted for positioning the lead in a lead position comprising at least one of near the patient'"'"'s stomach, near a selected nerve and near a nerve portion; and
, at least two electrodes disposed near the medical electrical lead distal end, the electrodes being electrically connected through the medical electrical lead to the INS to receive the at least one electrical stimulation signal and convey such signal to the electrode position;
wherein the electrical stimulation signal is provided in an amount and manner effective to at least of reduce the pH of the gastric acid in the patient and reduce the amount of gastric acid produced in the stomach of a patient.
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Accused Products
Abstract
A gastro-electric stimulation system comprises a INS for producing a electrical stimulation signal, at least one medical electrical lead, and at least two electrical contacts. The medical electrical lead has a proximal end and a distal end, the proximal end being connected to the INS, the distal end being adapted for placement in or near a patient'"'"'s stomach or appropriate nerve or nerve portion. The electrodes are disposed near the distal end of the medical electrical lead, and are The electrodes are electrically connected through the medical electrical lead to the INS to receive the electrical stimulation signal and convey such signal to the selected electrode implant position. The electrical stimulation signal is provided in an amount and manner adapted to decrease the pH of the gastric acid in the patient'"'"'s stomach and/or to decrease the amount of gastric acid produced thereby.
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Citations
48 Claims
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1. A gastro-electric stimulation system for at least one of reducing the pH of gastric acid in a stomach of a patient and reducing an amount of gastric acid produced in the stomach of the patient, comprising:
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a INS for producing at least one electrical stimulation signal;
at least one medical electrical lead having a proximal end and a distal end, the proximal end being connected to the INS, the distal end being adapted for positioning the lead in a lead position comprising at least one of near the patient'"'"'s stomach, near a selected nerve and near a nerve portion; and
,at least two electrodes disposed near the medical electrical lead distal end, the electrodes being electrically connected through the medical electrical lead to the INS to receive the at least one electrical stimulation signal and convey such signal to the electrode position;
wherein the electrical stimulation signal is provided in an amount and manner effective to at least of reduce the pH of the gastric acid in the patient and reduce the amount of gastric acid produced in the stomach of a patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A system for at least one of reducing the pH of gastric acid in a stomach of a patient and reducing an amount of gastric acid produced in the stomach of the patient, comprising:
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a pulse generator for generating stimulus pulses; and
a medical electrical lead adapted to deliver the stimulus pulses to a portion of a patient'"'"'s body;
wherein the stimulus pulses and medical electrical lead cooperate to provide electrical stimulation, to a selected stimulation site in the patient, in an amount and manner effective to at least one of reduce the pH of the gastric acid in the patient and reduce the amount of gastric acid produced in the stomach of the patient. - View Dependent Claims (11)
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12. A gastro-electric stimulator for at least one of reducing the pH of gastric acid in a stomach of a patient and reducing an amount of gastric acid produced in the stomach of the patient, comprising:
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a neuro-electrical stimulator for producing a stimulation signal;
at least one electrical lead having a proximal end and a distal end, the proximal end being connected to the neuro-electrical stimulator, the distal end being positionable in a selected lead position comprising at least one of near the patient'"'"'s stomach, near a selected nerve and near a nerve portion; and
,at least two electrodes disposed near the distal end of the electrical lead, the electrodes being electrically connected through the electrical lead to the neuro-electrical stimulator to receive the stimulation signal and convey such signal to the selected electrode position - View Dependent Claims (13, 14, 15, 16)
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17. A method for at least one of reducing the pH of gastric acid in a stomach of a patient and reducing an amount of gastric acid produced in the patient'"'"'s stomach, comprising:
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diagnosing gastric acid in a patient'"'"'s stomach comprising at least one of having an excessive pH and being produced in excessive quantities;
generating electrical stimulus pulses; and
delivering the stimulus pulses to at least one electrode stimulation site within the patient in an amount and manner effective to at least one of reduce the pH of the gastric acid the patient'"'"'s stomach and reduce the amount of gastric acid produced in patient'"'"'s stomach. - View Dependent Claims (18, 19, 20, 21, 22, 23)
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24. A method for at least one of reducing the pH of gastric acid in a stomach of a patient and reducing an amount of gastric acid produced in the patient'"'"'s stomach, comprising:
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providing an hermetically sealed implantable electrical pulse generator configured to provide at least one electrical stimulation pulse regime effective to at least one of reduce the pH of gastric acid and reduce the amount of gastric acid produced in the patient'"'"'s stomach;
providing at least a first implantable medical electrical lead configured for implantation adjacent, around or in a selected electrode stimulation site, the electrode stimulation site comprising at least one of the stomach, the vagus nerve, the plexus on the anterior superior and/or the anterior inferior pancreaticoduodenal arteries, the plexus on the inferior pancreaticoduodenal artery, the plexus on the jejunal artery, the superior mesenteric artery and plexus, the plexus on the gastroepiploic arteries, the celiac ganglia and plexus, the splenic artery and plexus, the left lesser thoracic splanchic nerve, the left greater thoracic splanchic nerve, the principal anterior gastric branch of the anterior vagal trunk, the left gastric artery and plexus, the celiac branch of the anterior vagal trunk, the anterior vagal trunk, proximal, distal or portions between the proximal and distal portions of the vagus nerve, the hepatic branch of the anterior vagal trunk, the right and/or left inferior phrenic arteries and plexus, the anterior posterior layers of the lesser omenium, the branch from the hepatic plexus to the cardia via the lesser omenium, the right greater thoracic splanchic nerve, the vagal branch from the hepatic plexus to the pylorus, the right gastric artery, the plexus and the intestine, and branches or portions thereof, the first lead comprising proximal and distal ends and at least one electrode;
implanting the first lead in tissue of the patient adjacent, around or in the selected electrode stimulation site;
operably connecting the proximal end of the at least first lead to the implantable pulse generator;
implanting the implantable pulse generator within the patient; and
delivering electrical stimulation pulses from the implantable pulse generator to the selected electrode stimulation site through the at least first lead and electrode, the pulses being provided in accordance with the electrical stimulation pulse regime to at least one of reduce the pH of the gastric acid and reduce the amount of gastric acid produced by the patient'"'"'s stomach. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48)
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Specification