Methods and apparatus for stenting comprising enhanced embolic protection coupled with improved protections against restenosis and thrombus formation
First Claim
1. Apparatus for stenting comprising:
- a stent having proximal and distal ends, and a lumen extending therebetween, the stent having a tubular body with a wall having a web structure configured for expansion from a collapsed delivery configuration to an expanded deployed configuration, the web structure comprising a plurality of interconnected, neighboring web patterns, each web pattern having a plurality of adjoining webs, each adjoining web comprising a central section interposed between first and second lateral sections, wherein the central section is substantially parallel to a longitudinal axis of the stent when in the collapsed delivery configuration, each of the first lateral sections joins the central section at a first angle, each of the second lateral sections joins the central section at a second angle, and adjacent ones of the neighboring web patterns have alternating concavity; and
a material attached to at least a portion of the stent between the proximal and distal ends.
2 Assignments
0 Petitions
Accused Products
Abstract
Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
194 Citations
40 Claims
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1. Apparatus for stenting comprising:
- a stent having proximal and distal ends, and a lumen extending therebetween, the stent having a tubular body with a wall having a web structure configured for expansion from a collapsed delivery configuration to an expanded deployed configuration,
the web structure comprising a plurality of interconnected, neighboring web patterns, each web pattern having a plurality of adjoining webs, each adjoining web comprising a central section interposed between first and second lateral sections, wherein the central section is substantially parallel to a longitudinal axis of the stent when in the collapsed delivery configuration, each of the first lateral sections joins the central section at a first angle, each of the second lateral sections joins the central section at a second angle, and adjacent ones of the neighboring web patterns have alternating concavity; and
a material attached to at least a portion of the stent between the proximal and distal ends. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
- a stent having proximal and distal ends, and a lumen extending therebetween, the stent having a tubular body with a wall having a web structure configured for expansion from a collapsed delivery configuration to an expanded deployed configuration,
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28. A method for stenting comprising the steps of:
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providing apparatus comprising a stent having proximal and distal ends, a lumen extending therebetween, and a material attached to at least a portion of the stent along defined planes or discrete points, the material comprising pores configured to enhance embolic protection and reduce a risk of restenosis and thrombus formation;
advancing the apparatus in a collapsed delivery configuration to a treatment site within a patient'"'"'s vessel;
expanding the apparatus to a deployed configuration in which the apparatus engages the patient'"'"'s vessel at the treatment site, the apparatus sealing dangerously large emboli at the treatment site against a wall of the patient'"'"'s vessel; and
promoting endothelial cell ingrowth through the pores of the material. - View Dependent Claims (29, 30, 31, 32, 33, 34, 35)
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36. Apparatus for stenting comprising:
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a stent having proximal and distal ends, and a lumen extending therebetween; and
a material attached to at least a portion of the stent between the proximal and distal ends, the material comprising pores along its entire length, the pores having diameters larger than about 30 μ
m and smaller than about 100 μ
m,wherein the material is attached to the stent along discrete points or defined planes. - View Dependent Claims (37)
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38. Apparatus for stenting comprising:
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a stent having proximal and distal ends, and a lumen extending therebetween; and
a material attached to at least a portion of the stent along discrete points or defined planes. - View Dependent Claims (39, 40)
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Specification