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Devices and methods for reducing scar tissue formation

  • US 20040241211A9
  • Filed: 02/11/2002
  • Published: 12/02/2004
  • Est. Priority Date: 11/06/2000
  • Status: Abandoned Application
First Claim
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1. A cytostatic anti-proliferative surgical wrap sheet of material adapted for being wrapped generally around tissues of a human body at the site of a surgical procedure, the sheet of material having a cytostatic anti-proliferative drug attached, the action of the cytostatic anti-proliferative drug being a reduction in the generation of scar tissue, the cytostatic anti-proliferative drug being selected from the group that includes sirolimus, anti-sense to c-myc (Resten-NG), tacrolimus (FK506), Everolimus and the any functional analog of sirolimus including:

  • SDZ-RAD, CCI-779, 7-epi-rapamycin, 7-thiomethyl-rapamycin, 7-epi-trimethoxyphenyl-rapamycin, 7-epi-thiomethyl-rapamycin, 7-demethoxy-rapamycin, 32-demethoxy, 2-desmethyl and proline.

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