Apparatus and method for hybridization and SPR detection

• US 20040241659A1
• Filed: 05/30/2003
• Published: 12/02/2004
• Est. Priority Date: 05/30/2003
• Status: Abandoned Application

• Current Assignee: Applied Biosystems LLC (Thermo Fisher Scientific Incorporated)
• Original Assignee: Applera Corporation (Thermo Fisher Scientific Incorporated)
• Inventors: Cox, Steven J., Oldham, Mark F., Schroth, Gary P., Haga, Douwe D., Recknor, Michael W., Wojtowicz, Janusz B., Ferea, Tracy L.
• Application Number:
  US10/448,803
• Publication Number:
  US 20040241659A1
• Time in Patent Office: Days
• US Class Current: 435/6
• CPC Class Codes: B01L 2200/026 Fluid interfacing between devices or objects, e.g. connectors, inlet details
• CPC Class Codes: B01L 2300/041 Connecting closures to device or container
• CPC Class Codes: B01L 2300/0636 Integrated biosensor, microarrays
• CPC Class Codes: B01L 2300/0877 Flow chambers
• CPC Class Codes: B01L 3/502 with fluid transport, e.g. in multi-compartment structures centrifugal-type cuvettes G01N21/07; analysis by separation into components G01N30/00; automatic analysers G01N35/00

Abstract

An apparatus and method for hybridization providing a chamber for hybridization and SPR detection. The hybridization chamber can have an inlet port and an outlet port. The chamber is adapted for SPR detection by a grating or by prism.

Claims

1-16. -16. (cancelled).

17. In combination, a floating body provided with a hull, an earthmoving device, means for supporting the earthmoving device along the outside of the hull, and means for moving the earthmoving device in a longitudinal direction along the outside of the hull for the purpose of carrying out operations on the water bed.

18. The combination according to claim 17, wherein the earthmoving device comprises at least one sand extraction plant.

19. The combination according to claim 18, wherein the sand extraction plant comprises a pump that is drivable by a motor, a suction line that is in fluid connection with the pump for extracting a sand/water mixture, and a discharge pipe for discharging the extracted sand/water mixture.

20. The combination according to claim 17, wherein the earthmoving device is suspended, and is movable along the hull by at least one cable.

21. The combination according to claim 20, further comprising at least one hoisting device for paying out or hauling in the cable.

22. The combination according to claim 21, further comprising a second hoisting device, and a second cable interacting with said second hoisting device for paying out or hauling in the second cable.

23. The combination according to claim 21, wherein at least one hoisting device is fitted on the earthmoving device.

24. The combination according to claim 21, wherein at least one hoisting device is fitted on the floating body.

25. The combination according to claim 24, wherein at least one hoisting device is movable along the hull of the floating body.

26. The combination according to claim 21, wherein the earthmoving device comprises at least one arm having a free end on which a hoisting device is situated.

27. The combination according to claim 26, wherein the earthmoving device comprises a frame, and each arm is connected in a swiveling manner to the frame.

28. The combination according to claim 17, wherein the earthmoving device is suspended from, and is movable along, the outside of the hull in the longitudinal and transverse directions by a rigid guide.

29. The combination according to claim 28, wherein the rigid guide is a rail which extends around the outer periphery of the hull.

30. Earthmoving device, comprising:

at least one sand extraction plant provided with a pump that is drivable by a motor, a suction line in fluid communication with the pump for extracting a mixture of sand and water, and a discharge pipe for discharging the extracted mixture of sand and water;

at least one cable for suspending the earthmoving device along the outside of a hull of a floating vessel; and

means for moving the earthmoving device in the longitudinal and transverse directions along the outside of the hull.

31. The earthmoving device according to claim 30, further comprising at least one hoisting device for paying out or hauling in the cable.

32. The earthmoving device according to claim 31, further comprising at least one arm having a free end on which the hoisting device is situated.

33. The earthmoving device according to claim 32, further comprising a frame, and each arm is connected in a swiveling manner to the frame.

34. Method for moving a floating body in a body of water whose depth is less than the draft of the floating body, comprising the following steps:

providing an earthmoving device for carrying out operations on the bed of the body of water;

suspending the earthmoving device from the outside of the floating body;

moving the earthmoving device along the outside of the floating body; and

carrying out the operations on the bed of the body of water at several positions along the floating body, for restoring and/or retaining the floating power of the floating body.

35. The method according to claim 34, further comprising forming a deepened bed part next to and/or underneath the floating body.

36. The method according to claim 35, further comprising refloating or bringing ashore the floating body.