Microneedle array module and method of fabricating the same
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Abstract
A microneedle array module is disclosed comprising a multiplicity of microneedles affixed to and protruding outwardly from a front surface of a substrate to form the array, each microneedle of the array having a hollow section which extends through its center to an opening in the tip thereof. A method of fabricating the microneedle array module is also disclosed comprising the steps of: providing etch resistant mask layers to one and another opposite surfaces of a substrate to predetermined thicknesses; patterning the etch resistant mask layer of the one surface for outer dimensions of the microneedles of the array; patterning the etch resistant mask layer of the other surface for inner dimensions of the microneedles of the array; etching unmasked portions of the substrate from one and the other surfaces to first and second predetermined depths, respectively; and removing the mask layers from the one and the other surfaces. One embodiment of the method includes the steps of: providing an etch resistant mask layer to the other surface of the substrate to a predetermined thickness; patterning the etch resistant mask layer of the other surface to define a reservoir region in the substrate; and etching away the unmasked reservoir region of the substrate to form a reservoir well in the other surface of the substrate. A layer of material may be provided to the other surface to enclose the reservoir well and a passageway is provided through the layer to the well region.
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Citations
33 Claims
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1-13. -13. (Canceled)
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14. A method of fabricating a microneedle array module comprising the steps of:
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providing etch resistant mask layers to one and another opposite surfaces of a substrate to predetermined thicknesses;
patterning the etch resistant mask layer of the one surface for outer dimensions of the microneedles of said array;
patterning the etch resistant mask layer of the other surface for inner dimensions of the microneedles of said array;
etching unmasked portions of said substrate from one and the other surfaces to first and second predetermined depths, respectively; and
removing the mask layers from the one and the other surfaces. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33)
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Specification