Hydrogel string medical device

• US 20040247867A1
• Filed: 03/25/2004
• Published: 12/09/2004
• Est. Priority Date: 03/25/2003
• Status: Abandoned Application

• Current Assignee: BioCure, Inc.
• Original Assignee: BioCure, Inc.
• Inventors: Chaouk, Hassan, Asfaw, Bruktawit T.
• Application Number:
  US10/809,140
• Publication Number:
  US 20040247867A1
• Time in Patent Office: Days
• US Class Current: 428/364
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12099 characterised by the location of the occluder
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 2017/00641 for closing fistulae, e.g. anorectal fistulae
• CPC Class Codes: A61B 2017/00654 entirely comprised between the two sides of the opening
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61M 2025/0057 Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
• CPC Class Codes: Y10T 428/2913 Rod, strand, filament or fiber

Abstract

A hydrogel string that is useful as a medical device and a method for forming a hydrogel string that utilizes a delivery device in which gelation of a prepolymer is initiated to form a hydrogel, which is then extruded from the device as the hydrogel string.

Claims

1. A method for forming a hydrogel string comprising the steps:

providing a delivery device having a gelation chamber;

providing a prepolymer composition that will form a hydrogel when brought into contact with a gelation initiator;

contacting the prepolymer with the gelation initiator in the gelation chamber so that it form a hydrogel in the gelation chamber; and

extruding the hydrogel from the delivery device as a hydrogel string.

2. The method of claim 1, wherein the delivery device is a catheter.

3. The method of claim 2, wherein the delivery device is a multilumen catheter.

4. The method of claim 1, wherein the delivery device is a catheter having at least two lumens and a gelation chamber at the distal end.

5. The method of claim 4, wherein the catheter is a coaxial catheter having an inner catheter and an outer catheter and the method further comprises the step of step of sliding the inner catheter within the outer catheter to increase or decrease the length of the gelation chamber.

6. The method of claim 1, wherein the prepolymer composition comprises at least two solutions that will form a hydrogel when combined in the gelation chamber.

7. The method of claim 1, wherein the hydrogel is extruded as prepolymer composition is moved into the gelation chamber.

8. The method of claim 1, wherein the delivery device is a coaxial dual lumen catheter and the inner catheter is slidable within the outer catheter so that the degree of formation of the hydrogel string as it exits the gelation chamber can be altered as the inner catheter is slid towards the distal end of the gelation chamber.

9. A hydrogel string formed by the method of claim 1.

10. A hydrogel string formed by the method of claim 5.

11. A hydrogel string formed by the method of claim 6.

12. A hydrogel string formed by the method of claim 8.