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Method for the simultaneous and direct determination of serum cholesterol in high an low density lipoproteins using infrared spectroscopy

  • US 20040248309A1
  • Filed: 08/02/2004
  • Published: 12/09/2004
  • Est. Priority Date: 09/12/2001
  • Status: Active Grant
First Claim
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1. A method of determining the concentration of at least one cardiovascular risk marker selected from the group consisting of High Density Lipoprotein cholesterol (HDL-C), Low Density Lipoprotein cholesterol (LDL-C), and oxidized LDL comprising:

  • subjecting a serum sample to infra-red light;

    collecting at least one spectrum of infrared light after interaction with the sample; and

    determining the concentration of the cardiovascular risk marker in the sample based on the intensity of spectral features or patterns over at least one spectral range selected from the group consisting of 900-1,500 cm

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    , 1500-1800 cm

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    , and 2800-3500 cm

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    .

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