Polyethylene glycol-modified semiconductor nanoparticles, method for producing the same, and material for biological diagnosis
First Claim
1. Polyethylene glycol-modified semiconductor nanoparticles comprising a structure having polyethylene glycol of a number average molecular weight of 300 to 20000 having a thiol group at one end, bonded via cadmium to II-VI semiconductor nanocrystals of a core-shell structure having a ZnX shell, wherein X stands for O, S, Se, or Te, wherein said semiconductor nanoparticles are water-soluble.
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Abstract
This invention provides PEG-modified semiconductor nanoparticles of which fluorescence intensity is effectively inhibited from lowering, which are capable of forming a stable dispersion in water, and which are capable of bonding easily with biomolecules having specific recognition, as well as methods for conveniently preparing such nanoparticles, and a material for biological diagnosis. The water-soluble PEG-modified semiconductor nanoparticles of the present invention includes a structure having PEG of a number average molecular weight of 300 to 20000 having a thiol group at one end, bonded via cadmium to II-VI semiconductor nanocrystals of a core-shell structure having a ZnX (wherein X stands for O, S, Se, or Te) shell.
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8 Claims
- 1. Polyethylene glycol-modified semiconductor nanoparticles comprising a structure having polyethylene glycol of a number average molecular weight of 300 to 20000 having a thiol group at one end, bonded via cadmium to II-VI semiconductor nanocrystals of a core-shell structure having a ZnX shell, wherein X stands for O, S, Se, or Te, wherein said semiconductor nanoparticles are water-soluble.
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