Reduced volume strip

• US 20040251132A1
• Filed: 06/02/2004
• Published: 12/16/2004
• Est. Priority Date: 06/06/2003
• Status: Abandoned Application

• Current Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Original Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Inventors: Leach, Christopher Philip, Beck, Erica Mary
• Application Number:
  US10/860,180
• Publication Number:
  US 20040251132A1
• Time in Patent Office: Days
• US Class Current: 204/403.01
• CPC Class Codes: C12Q 1/006 for glucose
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52

Abstract

A sensor for performing an electrochemical test for an analyte in a sample comprising a substrate, a conductive layer disposed on said substrate, one conductive layer comprising a reference electrode and at least one working electrode; an insulation layer disposed on at least a part of said conductive layer so as to expose a portion of said conductive layer; a reagent layer covering at least a part of said exposed portion of said conductive layer; and an adhesive layer defining at least part of a wall of a sample receiving chamber and wherein said adhesive layer covers at least a portion of said reagent layer.

Claims

1. A sensor for performing an electrochemical test for an analyte in a sample comprising:

a substrate;

a conductive layer disposed on said substrate, and wherein said conductive layer comprises a reference electrode and at least one working electrode;

an insulation layer disposed on at least a part of said conductive layer so as to expose a portion of said conductive layer;

a reagent layer covering at least a part of said exposed portion of said conductive layer; and

an adhesive layer defining at least part of a wall of a sample receiving chamber and further wherein said adhesive layer covers at least a portion of said reagent layer.

2. The electrochemical sensor of claim 1 in which said adhesive layer further comprises a water based pressure sensitive adhesive.

3. The electrochemical sensor of claim 1 in which said adhesive layer overlaps at least a part of said reagent layer.

4. The electrochemical sensor according to claim 1, in which said adhesive layer defines more than one wall of a sample chamber and at least two walls touch said reagent layer.

5. The electrochemical sensor of claim 3 in which at least two of said walls overlap with said reagent layer

7. The electrochemical sensor as in claim 1, wherein a width of a sample receiving chamber is between about 10 microns and 1.5 mm.

9. The electrochemical sensor as in claim 1, wherein said reagent layer comprises a material selected from the group consisting of a redox mediator, a redox enzyme, and a thromboplastin.

10. The electrochemical sensor as in claim 1, further comprises a top layer which is disposed on said adhesive layer to form a ceiling for said sample receiving chamber.

11. The electrochemical sensor as in claim 1, wherein said adhesive layer has a height between about 10 and 150 microns.

12. The electrochemical sensor as in claim 10, wherein said adhesive laser has a height between about 70 and 110 microns.

13. The electrochemical sensor as in claim 10, wherein said adhesive laser has a height between about 70 and 90 microns.

14. The electrochemical sensor as in claim 9, wherein said adhesive laser has a height between about 10 and 150 microns.

15. The electrochemical sensor as in claim 14, wherein said adhesive laser has a height between about 70 and 110 microns.

16. The electrochemical sensor as in claim 15, wherein said adhesive laser has a height between about 70 and 90 microns.

17. The electrochemical sensor as in claim 1, in which said reagent layer covers all of said exposed portion of said conductive layer.

18. The electrochemical sensor as in claim 1, wherein said conductive layer comprises a material selected from the group consisting of Au, Pd, Ir, Pt, Rh, stainless steel, doped tin oxide, and carbon.

19. The electrochemical sensor as in claim 1, wherein said substrate comprises a material selected from the group consisting of nylon, polyester, polycarbonate, polyimide, polyvinylchloride, polyethylene, polypropylene, and PETG.

20. The electrochemical sensor as in claim 1, wherein said adhesive is a pressure sensitive adhesive.

21. The electrochemical sensor as in claim 1, wherein said test determines a concentration of said analyte.

22. The electrochemical sensor as in claim 21, wherein said analyte is glucose.

23. The electrochemical sensor as in claim 1, wherein said test determines a coagulation time of a physiological fluid.

24. The electrochemical sensor as in claim 1, wherein said test strip is a disposable test strip.

25. An electrochemical sensor kit comprising:

said sensor as in claim 1

a meter which has a means for electrically interfacing with said test strip and a means for measuring glucose.

6. A sensor for performing an electrochemical test for an analyte in a sample comprising:

a substrate;

a conductive layer disposed on said substrate, and wherein said conductive layer comprises a reference electrode and at least one working electrode;

an insulation layer disposed on at least a part of said conductive layer so as to expose a portion of said conductive layer;

a reagent layer covering at least a part of said exposed portion of said conductive layer; and

an adhesive layer defining at least part of a wall of a sample receiving chamber, said wall having a lower edge lying inwards, with respect to a center of said sample receiving chamber, of at least a portion of an outer edge of said reagent layer so that a portion of said adhesive layer lies on top of a portion of said reagent layer.

8. The electrochemical sensor as in claim 6, which further comprises a width of a sample receiving chamber is between about 0.4 and 0.9 mm.

26. A method for making a sensor for performing an electrochemical test for an analyte in a sample comprising:

applying a conductive layer to a substrate, wherein said conductive layer comprises a reference electrode and at least one working electrode;

applying an insulation layer to at least a part of said conductive layer so as to expose a portion of said conductive layer;

applying a reagent layer which covers at least a part of said exposed portion of said conductive layer;

applying an adhesive layer which touches at least a portion of said reagent layer and defines at least part of a wall of a sample receiving chamber; and

applying a top layer to said adhesive layer to form a ceiling for said sample receiving chamber.