Methods and devices for creating electrical block at specific targeted sites in cardiac tissue

• US 20040254597A1
• Filed: 04/30/2004
• Published: 12/16/2004
• Est. Priority Date: 05/01/2003
• Status: Abandoned Application

• Current Assignee: Syntach AG
• Original Assignee: Sinus Rhythm Technologies, Inc.
• Inventors: Cornelius, Richard, Schwartz, Robert S., Swanson, William
• Application Number:
  US10/835,697
• Publication Number:
  US 20040254597A1
• Time in Patent Office: Days
• US Class Current: 606/167
• CPC Class Codes: A61B 17/205 Vaccinating by means of needles or other puncturing devices
• CPC Class Codes: A61B 17/3207 Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions A61B17/32037 takes precedence; endoscopic cutting instruments A61B17/320016
• CPC Class Codes: A61B 2017/00247 Making holes in the wall of the heart, e.g. laser Myocardial revascularization
• CPC Class Codes: A61B 2017/00256 Creating an electrical block
• CPC Class Codes: A61B 2017/320004 abrasive
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation

Abstract

The present invention provides a mechanical injury device having cutting elements for injuring tissue and thereby creating electrical block that can prevent atrial fibrillation. These cutting elements may preferably be removable, breakaway, or simply integral to the injury device and may be delivered, for example, by catheter or hand tool.

Claims

1. A device for causing injury to tissue comprising:

an arm having a proximal end and a distal end;

a roller rotatably disposed at said distal end of said arm;

at least one cutting element disposed on a peripheral surface of said roller; and

,

said at least one cutting element sized and shaped to cause injury to tissue at a target site.

2. A device as set forth in claim 1, further comprising:

a catheter body wherein said arm is connected to said catheter body; and

a sheath movably disposed on said catheter body, said sheath being sized to receive said arm and said roller.

3. A device as set forth in claim 2 wherein said arm is connected to said catheter body at a location spaced from a distal end of said catheter body such that said roller extends in a distal direction relative to said catheter body.

4. A device as set forth in claim 2, wherein said arm is connected to said catheter body at a location near a distal end of said catheter body such that said roller extends in a direction toward a proximal end of said catheter body.

5. A device as set forth in claim 1, wherein said arm is connected to a handle suitable for gripping by a human hand.

6. A device as set forth in claim 1, wherein said roller is a cylindrical roller.

7. A device as set forth in claim 1, wherein said roller is a spherical roller.

8. A device as set forth in claim 1, wherein said at least one cutting element is detachable from said roller so as to be embedded in tissue at said target site.

9. A device as set forth in claim 1, wherein said at least one cutting element comprises a plurality of cutting elements, at least one of which is detachable from said roller so as to be embedded in said target site.

10. A device as set forth in claim 8, wherein said detachable cutting element comprises a barb extending from a ring and wherein a post for receiving said ring is disposed on said periphery of said roller.

11. A device as set forth in claim 1, wherein said arm has a preset angular shape.

12. A device as set forth in claim 1, wherein said cutting element includes a coating to enhance scarring.

13. A device as set forth in claim 12, wherein said coating is selected from a group comprising glutaraldehyde, tetracycline, actinomycin, and polidocanol.

14. A device as set forth in claim 12, wherein said cutting element is hollow so as to allow a coating delivered through said cutting element to be injected into tissue as said cutting element contacts said tissue.

15. A method for causing tissue injury comprising:

identifying a target site;

placing a roller having at least one cutting element into contact with said target site;

manipulating said roller such that said at least one cutting element causes a region of tissue injury at said target site;

withdrawing said roller from said target site;

allowing said region of tissue injury to cause a desired physiological effect at said target site.

16. A method as set forth in claim 15, wherein the causing of a desired physiological effect includes causing a hemorrhage induction to create a scar.

17. A method as set forth in claim 15, wherein the causing of a desired physiological effect includes creating an electrical conduction block.

18. A method as set forth in claim 15, wherein the manipulating of said roller includes embedding at least one cutting element into said region of tissue injury.

19. A method as set forth in claim 15, wherein the placing of the roller is performed percutaneously.

20. A method as set forth in claim 15, wherein the placing of the roller is performed with a hand tool.

21. A method as set forth in claim 15, wherein said target site is an ostial opening of a pulmonary vein.

23. A method as set forth in claim 20, wherein the placing of said roller includes placing a roller having a plurality of cutting elements, at least one of which is releasable from said roller.

24. A method as set forth in claim 15 wherein said cutting element includes a coating to enhance scarring.

25. A method as set forth in claim 24 wherein said coating is selected from a group comprising glutaraldehyde, tetracycline, actinomicin, and polidocanol.

22. A method as set forth in 15, wherein the placing of said roller includes placing a roller having a plurality of cutting elements.

26. A device for causing tissue injury in a body lumen comprising:

a catheter having a proximal and distal end;

an expandable structure disposed at said distal end; and

,

a plurality of cutting elements disposed on said expandable structure such that said cutting elements contact tissue in said lumen when said structure is in an expanded state.

27. A device as set forth in claim 26 wherein said expandable structure is an expandable mesh.

28. A device as set forth in claim 27, wherein said mesh is a wire mesh.

29. A device as set forth in claim 26, wherein said expandable structure is sized and shaped for placement in a pulmonary vein.

30. A device as set forth in claim 26, wherein said cutting element includes a coating to enhance scarring.

31. A device as set forth in claim 30, wherein said coating is selected from a group comprising glutaraldehyde, tetracycline, actinomicin, and polidocanol.

32. A device for causing tissue injury comprising:

a tube having a fixation element disposed at a distal end of said tube;

a deployment arm connected to said tube;

a plurality of cutting elements disposable within said deployment arm.

a mechanism for ejecting at least one cutting element to a target tissue site when said fixation element has retained said tube in a desired position.

33. A device as set forth in claim 32, wherein said fixation element is an expandable mesh.

34. A device as set forth in claim 32, wherein said device is a catheter assembly.

35. A device as set forth in claim 32, wherein said cutting element includes a coating to enhance tissue inflammation.

36. A device as set forth in claim 32, wherein said cutting element includes a coating to enhance scarring.

38. A device as set forth in claim 35, wherein said coating is selected from a group comprising glutaraldehyde, tetracycline, actinomicin, and polidocanol.