Universal diagnostic platform

• US 20040260204A1
• Filed: 07/16/2004
• Published: 12/23/2004
• Est. Priority Date: 10/16/2001
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Agilent Technologies, Inc.
• Inventors: Boecker, Dirk, Freeman, Dominique M., Greenstein, Michael, Pittaro, Rick, Higgins, Michael C.
• Granted Patent: US 7,575,558 B2
• Time in Patent Office: Days
• US Class Current: 600/584
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150221 Valves
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/150755 Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
• CPC Class Codes: A61B 5/150854 long distance, e.g. between patient's home and doctor's office
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/15117 comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
• CPC Class Codes: A61B 5/15121 comprising piezos
• CPC Class Codes: A61B 5/15123 comprising magnets or solenoids
• CPC Class Codes: A61B 5/1519 comprising driving means, e.g. a spring, for propelling the piercing unit
• CPC Class Codes: A61M 2205/3576 with non implanted data transmission devices, e.g. using external transmitter or receiver
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: H04L 67/025 for remote control or remote monitoring of applications
• CPC Class Codes: H04L 67/1097 for distributed storage of data in networks, e.g. transport arrangements for network file system [NFS], storage area networks [SAN] or network attached storage [NAS]
• CPC Class Codes: H04L 67/12 specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
• CPC Class Codes: Y10S 128/903 Radio telemetry

Abstract

A portable medical analyzer comprising a sampling module with a sample port for receiving body fluid, an assay sensor module for analysis of the body fluid, an analytical detector module with detection of information from the assay, and a communications module for transferring the information to a remote location via a wired or wireless network.

Claims

1. A portable medical analyzer comprising:

a sampling module comprising a lancet, a driving mechanism, and a sample port, wherein said sampling port receives at least one body fluid from a tissue punctured with said lancet driven by said driving mechanism;

an assay sensor module housed in a cartridge, said cartridge comprising an interface with said sample port and at least one passage way to transport said body fluid to at least one assay sensor in said assay sensor module;

an analytical detector module comprising at least one analytical detector positioned to correspond to said assay sensor, said detector is adapted to detect information from said assay sensor; and

a communication module adapted to communicate with an information management system.

2. A portable medical analyzer according to claim 1, wherein:

said communication module comprises a transmitter adapted to transfer said information to a remote location.

3. A portable medical analyzer according to claim 1, wherein:

said communication module comprises a receiver adapted to communicate with a remote location.

4. A portable medical analyzer according to claim 1, wherein:

said sampling module is housed in said cartridge.

5. A portable medical analyzer according to claim 4, wherein:

said analytical detector module is adapted to couple with said cartridge via a digital media standard interface.

8. A portable medical analyzer according to claim 1, wherein:

said transmitter is adapted to at least one interface chosen from radio frequency, infrared and standard ports.

9. A portable medical analyzer according to claim 1, further comprising:

an information storage unit for storing said information locally on said portable medical analyzer.

6. (Canceled).

7. (Canceled).

10. A method for portable medical analysis comprising:

obtaining a body fluid;

housing said body fluid within a cartridge comprising an assay sensor module;

positioning said cartridge into an analytical detector module;

obtaining information from said analytical detector module;

displaying said information locally on a display within said communication module; and

transferring said information to a remote location via a communication module.

11. (Canceled).

12. A portable medical analyzer comprising:

a sampling module comprising a sample port for receiving at least one body fluid, said sampling module housed in a cartridge;

an assay sensor module housed in said cartridge, said assay sensor module comprising at least one assay sensor adapted to at least one assay for said body fluid;

an analytical detector module comprising at least one signal processor and circuitry for processing of signals from at least one detector corresponding to said assay sensor, said detector adapted to detect information from said assay;

a communication module coupled to said signal processor, said communication module comprising a transmitter and receiver in communication with an information management system.

13. A portable medical analyzer according to claim 12, wherein:

said communication module is adapted to displaying said information locally on said portable medical analyzer.

14. A portable medical analyzer according to claim 12, wherein:

said communication module is adapted to displaying historical data locally on portable medical analyzer.

15. A portable medical analyzer according to claim 12, wherein:

said transmitter is adapted to at least one interface chosen from radio frequency, infrared and standard ports.

16. A portable medical analyzer according to claim 12, wherein:

said transmitter is adapted to communicate with a remote database.

17. A portable medical analyzer according to claim 12, wherein:

said communication module further comprises a storage unit for storing said information locally on said portable medical analyzer.

18. A portable medical analyzer according to claim 12, wherein:

said information management system comprises a system for brokering medical data.

19. A portable medical analyzer according to claim 12, wherein:

said information management system comprises a system for patient management.

20. A portable medical analyzer according to claim 12, wherein:

said information management system comprises a system for administering said portable medical analyzer.

21. A portable medical analyzer comprising:

a sampling module comprising a sample port for receiving at least one body fluid directly from a tissue, said sampling module housed in a cartridge;

an assay sensor module housed in said cartridge, said assay sensor module comprising at least one assay sensor adapted to at least one assay for said body fluid;

an analytical detector module comprising at least one signal processor and circuitry for processing of signals from at least one detector corresponding to said assay sensor, said detector adapted to detect information from said assay; and

a communication module coupled to said signal processor, said communication module comprising a transmitter and receiver in communication with an information management system, wherein said information management system comprises a means for brokering medical data;

wherein interfacing the cartridge with the sample port includes breaking a pressure seal on the cartridge.

22. A portable medical analyzer comprising:

a lancet within a cartridge;

a lancet driver for advancing said lancet to puncture tissue;

a sample pathway for receiving at least one body fluid directly from a tissue puncture formed by said lancet, said pathway contained within the cartridge;

at least one assay sensor housed in said cartridge, said sensor adapted for at least one assay for said body fluid received by said sample pathway;

an analytical detector comprising at least one signal processor and circuitry for processing of signals from at least one detector corresponding to said assay sensor, said detector adapted to detect information from said assay; and

a communication module coupled to said signal processor, said communication module comprising a transmitter and receiver in communication with an information management system;

wherein a pressure seal on the cartridge is broken, via interface with the analytical detector, during transfer of the body fluid to the assay sensor.

23. A portable medical analyzer according to claim 22, wherein:

said communication module comprises a transmitter adapted to transfer said information to a remote location.

24. A portable medical analyzer according to claim 22, wherein:

said communication module comprises a receiver adapted to communicate with a remote location.

25. A portable medical analyzer according to claim 22, wherein:

communication module has a transmitter using one of the following for transmission of information to a remote location;

infrared or radio frequency signals.

26. A portable medical analyzer according to claim 22, wherein:

communication module includes at least one of the following;

a processor, display, RF chip, antenna, an operating system, RAM, DRAM, or a PCMCIA interface.

27. A portable medical analyzer according to claim 22, wherein:

said communication module is adapted to couple with said analytical detector via a standard port.

28. A portable medical analyzer according to claim 22, wherein:

said transmitter is adapted to include at least one interface chosen from radio frequency, infrared and standard ports.

29. A portable medical analyzer according to claim 22, further comprising:

an information storage unit for storing said information locally on said portable medical analyzer.

30. A portable medical analyzer according to claim 22, wherein said driver comprises an electromechanical lancet driver.

31. A portable medical analyzer according to claim 22 wherein said driver comprises an electrical lancet driver.