Container, method and system for cryptopreserved material
First Claim
1. A tissue storage container, comprising:
- a base plate comprised of a first polymeric material and comprising an upper surface and an opposite lower surface wherein the lower surface is non-planar with a distinct configuration;
a substantial cylindrical wall connected to and extending from the upper surface of the base plate to an upper end with threadings positioned therein, the wall comprised of the first polymeric material;
a cover comprised of a second polymeric material different from the first polymeric material, the cover comprising a circular portion having threadings thereon which match and screw to the threadings on the wall and the cover comprising an upper surface which is non-planar and comprise a distant configuration which is a mirror image of the lower surface of the base plate;
a tissue sample positioned in the container;
wherein the first polymeric material and second polymeric material comprise physical characteristics allowing the container to be frozen and thawed repeatedly without lose of structural integrity and while maintaining a substantially air tight seal while the cover is in place on the threadings of the wall.
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Accused Products
Abstract
Containers that are suitable for long-term and efficient storage, tracking, and manual or robotic manipulation of cryopreserved biological materials, in particular human tissue samples, are disclosed herein along with systems comprised of multiple containers and methods of using such. According to one exemplary embodiment disclosed herein, a container may include a receptacle and a plurality of projections. The receptacle may include a lower wall and a side wall. The side wall may have an inner surface. The plurality of projections may extend upward along and outward from the inner surface of the side wall. The plurality of projections may define a region for receiving a sample having an orientation and may be shaped and arranged to inhibit a change in the orientation of the sample when stored in the container.
60 Citations
26 Claims
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1. A tissue storage container, comprising:
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a base plate comprised of a first polymeric material and comprising an upper surface and an opposite lower surface wherein the lower surface is non-planar with a distinct configuration;
a substantial cylindrical wall connected to and extending from the upper surface of the base plate to an upper end with threadings positioned therein, the wall comprised of the first polymeric material;
a cover comprised of a second polymeric material different from the first polymeric material, the cover comprising a circular portion having threadings thereon which match and screw to the threadings on the wall and the cover comprising an upper surface which is non-planar and comprise a distant configuration which is a mirror image of the lower surface of the base plate;
a tissue sample positioned in the container;
wherein the first polymeric material and second polymeric material comprise physical characteristics allowing the container to be frozen and thawed repeatedly without lose of structural integrity and while maintaining a substantially air tight seal while the cover is in place on the threadings of the wall. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 23, 24, 25, 26)
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11. A tissue storage system, comprising:
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a first container; and
a second container;
wherein the first container and the second container are each comprised of;
a base plate comprised of a first polymeric material and comprising an upper surface and an opposite lower surface wherein the lower surface is non-planar with a distinct configuration;
a substantial cylindrical wall connected to and extending from the upper surface of the base plate to an upper end with threadings positioned therein, the wall comprised of the first polymeric material;
a cover comprised of a second polymeric material different from the first polymeric material, the cover comprising a circular portion having threadings thereon which match and screw to the threadings on the wall and the cover comprising an upper surface which is non-planar and comprise a distant configuration which is a mirror image of the lower surface of the base plate;
a tissue sample positioned in the container;
wherein the first polymeric material and second polymeric material comprise physical characteristics allowing the container to be frozen and thawed repeatedly without lose of structural integrity and while maintaining a substantially air tight seal while the cover is in place on the threadings of the wall; and
further wherein the lower surface of the base of the first container is in contact with the upper surface of the cover of the second container and the distinct configurations of each allows the containers to be stacked on each other. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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Specification