Biosensor for monitoring an analyte content with a partial voltage generated therefrom

• US 20050000806A1
• Filed: 07/01/2003
• Published: 01/06/2005
• Est. Priority Date: 07/01/2003
• Status: Active Grant

• Current Assignee: Intellectual Ventures I LLC (Intellectual Ventures LLC)
• Original Assignee: Transpacific IP Group Limited
• Inventors: Hsieh, Jun-Wei
• Granted Patent: US 7,347,925 B2
• Time in Patent Office: Days
• US Class Current: 204/403.10
• CPC Class Codes: G01N 33/48785 Electrical and electronic details of measuring devices for physical analysis of liquid biological material not specific to a particular test method, e.g. user interface or power supply

Abstract

A biosensor for monitoring an analyte content with a partial voltage generated therefrom is provided. The present biosensor includes a chip having a resistance R_s, a power source, and a microprocessor. The power source is used for supplying an applied voltage on the chip. The chip generates a time-dependent response current in response to a content of an analyte of a specimen applied thereon upon supplying the applied voltage on the chip. The microprocessor receives a time-dependent partial voltage caused from the chip due to the time-dependent response current, and determines the content of the analyte in accordance with the time-dependent partial voltage. The present biosensor is provided with fewer elements than a conventional one. A purpose of cost down is thus obtained.

Claims

1. A biosensor for monitoring an analyte content with a partial voltage generated therefrom, comprising:

a chip generating a time-dependent response current in response to a content of an analyte of a specimen applied thereon upon supplying an applied voltage on said chip;

a power source for supplying said applied voltage on said chip; and

a microprocessor for receiving a time-dependent partial voltage caused from said chip due to said time-dependent response current, and determining the content of the analyte in accordance with said time-dependent partial voltage.

2. The biosensor of claim 1, further comprising an analog to digital converter for converting said time-dependent partial voltage to a digital form for sending to said microprocessor.

3. The biosensor of claim 1, further comprising a resistor with one end thereof serially connected to said chip and the other end thereof connected to a ground.

4. The biosensor of claim 2, further comprising a resistor with one end thereof serially connected to said chip and the other end thereof connected to a ground.

5. The biosensor of claim 3, wherein said resistor is a variable resistor.

6. The biosensor of claim 4, wherein said resistor is a variable resistor.

7. The biosensor of claim 1, wherein said microprocessor has a mapping table of rising time versus content of the analyte established therein, a rising time is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said mapping table.

8. The biosensor of claim 1, wherein said microprocessor has a mapping table of peak voltage versus content of the analyte established therein, a peak voltage is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said mapping table.

9. The biosensor of claim 1, wherein said microprocessor has a mapping table of rising time versus prescribed curve of the analyte established therein, a rising time is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said prescribed curve corresponding thereto.

10. The biosensor of claim 1, wherein said microprocessor has a mapping table of peak voltage versus prescribed curve of the analyte established therein, a peak voltage is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said prescribed curve corresponding thereto.

11. The biosensor of claim 3, wherein said microprocessor has a mapping table of rising time versus content of the analyte established therein, a rising time is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said mapping table.

12. The biosensor of claim 3, wherein said microprocessor has a mapping table of peak voltage versus content of the analyte established therein, a peak voltage is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said mapping table.

13. The biosensor of claim 3, wherein said microprocessor has a mapping table of rising time versus prescribed curve of the analyte established therein, a rising time is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said prescribed curve corresponding thereto.

14. The biosensor of claim 3, wherein said microprocessor has a mapping table of peak voltage versus prescribed curve of the analyte established therein, a peak voltage is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said prescribed curve corresponding thereto.

15. The biosensor of claim 4, wherein said microprocessor has a mapping table of rising time versus content of the analyte established therein, a rising time is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said mapping table.

16. The biosensor of claim 4, wherein said microprocessor has a mapping table of peak voltage versus content of the analyte established therein, a peak voltage is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said mapping table.

17. The biosensor of claim 4, wherein said microprocessor has a mapping table of rising time versus prescribed curve of the analyte established therein, a rising time is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said prescribed curve corresponding thereto.

18. The biosensor of claim 4, wherein said microprocessor has a mapping table of peak voltage versus prescribed curve of the analyte established therein, a peak voltage is obtained from said time-dependent partial voltage and then the content of the analyte is determined in accordance with said prescribed curve corresponding thereto.

19. The biosensor of claim 1, wherein the analyte to be monitored depends on an enzyme of said chip.

20. The biosensor of claim 4, wherein the analyte to be monitored depends on an enzyme of said chip.