Single photon emission computed tomography system

• US 20050001170A1
• Filed: 06/18/2004
• Published: 01/06/2005
• Est. Priority Date: 04/14/1999
• Status: Active Grant

• Current Assignee: HighBrook Holdings, LLC
• Original Assignee: Jack E. Juni
• Inventors: Juni, Jack E.
• Granted Patent: US 7,105,825 B2
• Time in Patent Office: Days
• US Class Current: 250/363.40
• CPC Class Codes: A61B 6/037 Emission tomography
• CPC Class Codes: A61B 6/5258 involving detection or reduction of artifacts or noise
• CPC Class Codes: G01T 1/1644 using an array of optically separate scintillation elements permitting direct location of scintillations G01T1/1645 takes precedence
• CPC Class Codes: G01T 1/1648 Ancillary equipment for scintillation cameras, e.g. reference markers, devices for removing motion artifacts, calibration devices adapted for flow studies G01T1/1647
• CPC Class Codes: G01T 1/166 involving relative movement between detector and subject scanners in general without using scintigraphy G01T1/2964
• CPC Class Codes: G21K 1/025 using multiple collimators, e.g. Bucky screens; other devices for eliminating undesired or dispersed radiation

Abstract

A single photon emission computed tomography system includes a base for supporting a patient and a detector assembly adjacent the field of view. The detector assembly detects photon strikes from the field of view. A photon-blocking member is disposed between the field of view and the detector and has an aperture slot that allows passage of photons aligned with the slot. A collimating assembly includes a plurality of collimating vanes formed of photon-attenuating material. A support assembly supports the collimating assembly and includes a first support member and a second support member with the collimating assembly being disposed therebetween. An adjustment assembly includes a first adjuster operable to adjust a first distance between the collimating assembly and the first support member and a second adjuster operable to adjust a second distance between the collimating assembly and the second support member.

Claims

1. A single photon emission computed tomography system for producing multiple tomographic images of the type representing a three-dimensional distribution of a photon-emitting radioisotope, the system comprising:

a base including a patient support for supporting a patient such that a portion of the patient is located in a field of view, a longitudinal axis being defined through the field of view;

a detector assembly adjacent the field of view, the detector assembly including a photon-responsive detector operable to detect if a photon strikes the detector, the detector assembly operable to detect photons emitted from the portion of the patient located in the field of view;

a photon-blocking member disposed between the field of view and the detector, the blocking member having an aperture slot defined therethrough for passage of photons aligned with the aperture slot, a line of response being defined from the detector through the aperture;

a collimating assembly including a plurality of collimating vanes formed of photon-attenuating material;

a support assembly for supporting the collimating assembly, the support assembly including a first support member and a second support member, the second support member being spaced from the first support member, the collimating assembly being disposed between the support members such that a first distance is defined between the collimating assembly and the first support member and a second distance is defined between the collimating assembly and the second support member; and

an adjustment assembly including a first adjustor operable to adjust the first distance and a second adjustor operable to adjust the second distance.

2. The system according to claim 1, wherein the collimating assembly has a front face directed toward the field of view and a back face directed away from the field of view, the first adjustor comprising a first pair of adjusting members each extending between the first support member and the collimating assembly, one of the adjusting members being closer to the front face of the collimating assembly than the other adjusting member is to the front face.

3. The system according to claim 2, wherein the second adjustor comprises a second pair of adjusting members each extending between the first support member and the collimating assembly, one of the adjusting members being closer to the front face of the collimating assembly than the other adjusting member is to the front face, the first and second pairs of adjusting members cooperating to be operable to adjust the first distance and the second distance and an angle of the collimating assembly relative to the support assembly.

4. The system according to claim 1, wherein the support members are generally coextensive with each having a fixed end supported by the base and a free end spaced therefrom, the collimating assembly having a first end adjacent the base and a second end adjacent the free ends of the support members, the first adjustor comprising a first plurality of adjusting members extending between the first support member and the collimating assembly, the second adjustor comprising a second plurality of adjusting members extending between the second support member and the collimating assembly, the adjusting members cooperating to adjust the position of the collimating assembly relative to the support members.

5. The system according to claim 4, wherein the first plurality of adjusting members are spaced apart between the fixed and free ends of the first support member and the second plurality of adjusting members are spaced apart between the fixed and free ends of the second support member.

6. The system according to claim 5, wherein the collimating assembly has a front face directed toward the field of view and a back face directed away from the field of view, the first plurality of adjusting members including a front set and a back set, the first set being closer to the front face of the collimating assembly than the back set is to the front face of the collimating assembly.

7. The system according to claim 6, wherein the second plurality of adjusting members including a front set and a back set, the first set being closer to the front face of the collimating assembly than the back set is to the front face of the collimating assembly.

8. The system according to claim 4, wherein the support members are generally arcuate and generally disposed in planes perpendicular to the longitudinal axis, the support members extending generally arcuately at least partially about the field of view.

9. The system according to claim 1, wherein the support members are each generally flat members.

10. The system according to claim 1, wherein the support members are generally coextensive.

11. The system according to claim 1, wherein the support assembly has a fixed end supported by the base and a free end spaced therefrom.

12. The system according to claim 1, wherein the support assembly further comprises a plurality of tension members extending between the first and second support members, each tension member having a first end interconnected with the first support member and a second end interconnected with the second support member, the tension members being adjustable such that the distance between the first and second ends is adjusted.

13. The system according to claim 12, wherein the support members each have a fixed end supported by the base and a free end spaced therefrom.

14. The system according to claim 13, wherein the tension members are spaced apart between the fixed and second ends of the support members.

15. The system according to claim 14, wherein at least some of the tension members are angled such that the first end is farther from the fixed ends of the support members than the second end is from the fixed ends of the support member and others of the tension members are angled such that the second end is farther from the fixed ends of the support members than the first end is from the fixed end of the support members.

16. The system according to claim 1, wherein the longitudinal axis is generally vertical and the support assembly is disposed generally in a plane perpendicular to the longitudinal axis such that the first support member is an upper support member and the second support member is a lower support member.

17. The system according to claim 1, wherein the collimating assembly comprises a stack of alternating sheets of photon-blocking material and sheets of radiolucent material, the sheets of photon-blocking material defining the collimating vanes.

18. The system according to claim 1, further comprising a displacement actuator operable to move one of the detector and the photon-blocking member relative to the other of the detector and the photon-blocking member such that the aperture is displaced relative to the detector and the line of response is swept across at least a portion of the field of view.

19. The system according to claim 1, wherein the portion of the patient in the field of view is the patient'"'"'s torso, the longitudinal axis being generally vertical, such that the patient'"'"'s torso extends generally vertically with the patient'"'"'s head substantially higher than the patient'"'"'s hips.

20. The system according to claim 19, wherein the base comprises a chair-like structure having a generally horizontal bottom portion for supporting the patient'"'"'s hips and a generally vertical back portion of supporting the patient'"'"'s back.

21. The system according to claim 1, wherein the support assembly is generally arcuate and at least partially surrounds the field of view.

22. The system according to claim 1, wherein the collimating assembly are disposed between the photon-blocking member and the detector.

23. The system according to claim 1, wherein a radiolucent material is disposed between the vanes of the collimating assembly.

24. The system according to claim 1, wherein the collimating vanes are generally perpendicular to the longitudinal axis.

25. The system according to claim 1, wherein the collimating vanes are angled with respect to the longitudinal axis.

26. The system according to claim 1, wherein the aperture slot is generally parallel to longitudinal axis.

27. The system according to claim 1, wherein the aperture slot is generally perpendicular to at least some of the vanes.

28. An imaging system comprising:

a base;

a detector assembly for imaging a field of view, the detector assembly including a photon-responsive detector operable to detect if a photon strikes the detector, the detector assembly operable to detect photons emitted from the field of view;

a collimating assembly including a plurality of collimating vanes formed of photon-attenuating material;

a support assembly for supporting the collimating assembly, the support assembly including a first support member and a second support member, the second support member being spaced from the first support member, the collimating assembly being disposed between the support members such that a first distance is defined between the collimating assembly and the first support member and a second distance is defined between the collimating assembly and the second support member; and

an adjustment assembly including a first adjustor operable to adjust the first distance and a second adjustor operable to adjust the second distance.

29. A method of rebinning tomographic image data from a radial imaging system such that the data corresponds to data obtained from a traditional gamma camera of the type obtaining readings while located at a plurality of positions around a field of view, the field of view having a longitudinal axis defined therethrough, the traditional gamma camera having a sensing face with a central line parallel to the longitudinal axis, a position line being defined perpendicularly between the longitudinal axis and the central line, a sensing plane being defined as containing the position line and perpendicular to the longitudinal axis, a baseline being defined as perpendicular to the longitudinal axis and contained in the sensing plane, the angular position of the traditional gamma camera being defined as the angle, θ

, between the baseline and the position line, the traditional gamma camera being operable to detect photon strikes on the sensing face, each strike in the sensing plane being located at a distance, r, from the center line, the rebinning method comprising;

providing a radial imaging system comprising;

a base including a patient support for supporting a patient such that a portion of the patient is located in the field of view;

a generally arcuate detector assembly adjacent the field of view, the detector assembly including a photon-responsive detector operable to detect if a photon strikes the detector, the detector assembly being further operable to identify the position of the detector strike along the arcuate detector assembly;

a photon-blocking member disposed between the field of view and the detector, the blocking member having an aperture slot defined therethrough for passage of photons aligned with the aperture slot, a line of response being defined from the detector through the aperture;

a collimating assembly including a plurality of generally parallel collimating vanes formed of photon-attenuating material, the vanes being spaced apart so as to define a plurality of gaps; and

a displacement actuator operable to move one of the detector and the photon-blocking member relative to the other of the detector and the photon-blocking member such that the aperture is displaced relative to the detector and the line of response is swept across at least a portion of the field of view;

obtaining a plurality of detector readings associated with a plurality of photon strikes generally in the sensing plane, each reading including an intensity;

determining the position of each reading from the detector assembly, the position including a radius, R_det, from the center line of the field of view and an angular position, Ψ

, relative to the baseline;

determining the position of the aperture slot for each reading, the position including a radius, R_app, from the center line of the field of view and an angular position, φ

, relative to the baseline;

for each combination of r and θ

for a traditional gamma camera, calculating the corresponding value of Ψ and

φ

using the formulas

$\begin{array}{c}\mathrm{\varphi <br><br>}=\arcsin <br><br>\left(\frac{r}{R_{\mathrm{app}}}\right)-\mathrm{\theta <br><br>},\mathrm{and}\\ \mathrm{\Psi <br><br>}=\arcsin <br><br>\left(\frac{r}{R_{\det }}\right)-\mathrm{\theta <br><br>}\end{array}$

for each combination of r and θ

, storing the intensity value associated with the corresponding positions φ

, Ψ

, R_app and R_det.

30. The method according to claim 29, further comprising the step of providing a computing device and utilizing the computing device to perform the calculating and storing steps.

31. The method according to claim 29, further comprising the step of defining additional sensing planes and obtaining detector readings for each of the additional sensing planes.

32. A calibration source for a single photon emission computed tomography system of the type having:

a base including a patient support for supporting a patient such that a portion of the patient is located in a field of view, a longitudinal axis being defined through the field of view;

a detector assembly adjacent the field of view, the detector assembly including a photon-responsive detector operable to detect if a photon strikes the detector, the detector assembly operable to detect photons emitted from the portion of the patient located in the field of view;

a photon-blocking member disposed between the field of view and the detector, the blocking member having an aperture slot defined therethrough for passage of photons aligned with the aperture slot, a line of response being defined from the detector through the aperture;

a collimating assembly including a plurality of generally parallel collimating vanes formed of photon-attenuating material, the vanes being spaced apart so as to define a plurality of gaps, the plurality of vanes being disposed between the detector and the field of view such that only photons passing through one of the gaps can travel from the field of view to the detector; and

a displacement actuator operable to move one of the detector and the photon-blocking member relative to the other of the detector and the photon-blocking member such that the aperture is displaced relative to the detector and the line of response is swept across at least a portion of the field of view;

the calibration source comprising;

a radiation shield member formed of a radiation blocking material, the shield member having a front face and a back face; and

an elongated radiation source sized to fit adjacent the aperture in the photon blocking member, the radiation source being disposed adjacent the front face of the shield member.

33. The calibration source according to claim 32, wherein the front face of the shield member is concave.

34. The calibration source according to claim 32, wherein the radiation source is generally cylindrical.

35. The calibration source according to claim 32, wherein the radiation source is a layer or coating of radioactive material on the front face of the shield member.

36. In combination, a single photon emission computed tomography system for imaging a field of view and a calibration source for the system, the single photon emission computed tomography system comprising:

a detector assembly adjacent the field of view, the detector assembly including a photon-responsive detector operable to detect if a photon strikes the detector;

a photon-blocking member disposed between the field of view and the detector, the blocking member having an aperture slot defined therethrough for passage of photons aligned with the aperture slot, a line of response being defined from the detector through the aperture, the blocking member having a front face directed toward the field of view and a back face directed toward the detector assembly;

a collimating assembly including a plurality of generally parallel collimating vanes formed of photon-attenuating material, the vanes being spaced apart so as to define a plurality of gaps, the plurality of vanes being disposed between the detector and the field of view such that only photons passing through one of the gaps can travel from the field of view to the detector; and

a displacement actuator operable to move one of the detector and the photon-blocking member relative to the other of the detector and-the photon-blocking member such that the aperture is displaced relative to the detector and the line of response is swept across at least a portion of the field of view;

the calibration source having an installed position for calibrating the system and a non-installed position wherein the calibration source is separated from the system, the calibration source comprising;

a support configured to be disposed adjacent the front face of the blocking member and adjacent the aperture when the calibration source is in the installed position;

a radiation shield member formed of a radiation blocking material, the shield member having an inner face and an outer face, the shield member being interconnected with the support member such that the inner face is directed toward the aperture when the calibration source is in the installed position; and

a radiation source sized to fit adjacent the aperture, the radiation source being disposed on the inner face of the shield member such that when the calibration source is in the installed position, the radiation source is disposed adjacent the aperture and radiation from the radiation source radiates through the aperture.

37. The combination according to claim 36, wherein the tomography system further includes a holder for receiving the calibration source in the installed position, the holder comprising a slot for receiving the support of the calibration source.

38. The combination according to claim 36, wherein the tomography system further comprises a support assembly for supporting the photon blocking member, the support assembly including a first support member and a second support member, the second support member being spaced from the first support member, the photon blocking member being disposed between the support members, an opening being defined in one of the support members, a holder for receiving the calibration source being disposed between the support members and generally aligned with the opening such that the calibration source may be inserted through the opening into the holder such that the calibration source is in the installed position.

39. The combination according to claim 38, wherein the opening is spaced from the photon blocking member and the holder is pivotally attached to one of the support members such that in can pivot from a source receiving position aligned with the opening and a calibration position wherein the source is adjacent the photon blocking member.

40. The combination according to claim 36, wherein the inner face of the shield member is concave.

41. The combination according to claim 36, wherein the radiation source is generally cylindrical.

42. The combination according to claim 36, wherein the radiation source is a layer or coating of radioactive material on the front face of the shield member.

43. A method of calibrating a single photon emission computed tomography system comprising the steps of:

providing a single photon emission computed tomography system comprising;

a base including a patient support for supporting a patient such that a portion of the patient is located in a field of view, a longitudinal axis being defined through the field of view;

a detector assembly adjacent the field of view, the detector assembly including a photon-responsive detector operable to detect if a photon strikes the detector, the detector assembly operable to detect photons emitted from the portion of the patient located in the field of view;

a photon-blocking member disposed between the field of view and the detector, the blocking member having an aperture slot defined therethrough for passage of photons aligned with the aperture slot, a line of response being defined from the detector through the aperture, the blocking member having a front face directed toward the field of view and a back face directed toward the detector assembly;

a collimating assembly including a plurality of generally parallel collimating vanes formed of photon-attenuating material, the vanes being spaced apart so as to define a plurality of gaps, the plurality of vanes being disposed between the detector and the field of view such that only photons passing through one of the gaps can travel from the field of view to the detector; and

a displacement actuator operable to move one of the detector and the photon-blocking member relative to the other of the detector and the photon-blocking member such that the aperture is displaced relative to the detector and the line of response is swept across at least a portion of the field of view;

providing a calibration source comprising;

a radiation shield member formed of a radiation blocking material, the shield member having an inner face and an outer face; and

an elongated radiation source sized to fit adjacent the aperture in the photon blocking member, the radiation source being disposed adjacent the front face of the shield member;

positioning the calibration source adjacent the aperture in the photon blocking member on the front face of the photon blocking member such that the inner face of the radiation shield member faces the aperture and radiation from the source travels through the aperture; and

detecting photon strikes on the detector from the radiation source.

44. The method according to claim 43, further comprising moving the photon blocking member relative to the detector.

45. The method according to claim 43, wherein the photon blocking member further comprises a plurality of apertures, the method further comprising providing additional calibration sources and positioning one calibration source adjacent each aperture.

46. A medical imaging device comprising:

a base including a patient support for supporting a patient such that a portion of the patient is located in a field of view, a longitudinal axis being defined through the field of view;

a generally arcuate imaging section adjacent the field of view and disposed generally in a plane perpendicular to the longitudinal axis, the section extending generally arcuately at least partially about the field of view between a fixed end supported by the base and a free end spaced therefrom, the generally arcuate imaging section including;

a collimating assembly including a plurality of generally parallel collimating vanes formed of photon-attenuating material; and

a support assembly comprising;

a first support member disposed generally in a plane perpendicular to the longitudinal axis, the first support member having a fixed end supported by the base and a free end spaced therefrom;

a second support member spaced from the first support member by a distance and being generally parallel to the first support member, the second support member being generally coextensive with the first support member and having a fixed end supported by the base and a free end spaced therefrom;

the collimating assembly being disposed between the first and second support members; and

a plurality of tension members extending between the first and second support members, the tension members being spaced apart between the fixed and free ends of the support members, each tension member having a first end interconnected with the first support member and a second end interconnected with the second support member, the tension members being adjustable such that the distance between the first and second ends is adjusted.

47. The device according to claim 46, wherein at least some of the tension members are angled such that one of the ends is farther from the fixed end of the imaging section than the other end is from the fixed end of the imaging section.

48. The device according to claim 47, wherein some the angled tension members are positioned such that the first end is farther from the fixed end of the imaging section than the second end is from the fixed end of the imaging section and others are angled such that the second end is farther from the fixed end of the imaging section than the first end is from the fixed end of the imaging section.

49. The device according to claim 47, wherein adjusting the distance between the first and second ends of the tension members adjusts the longitudinal position of the free end of the imaging section relative to the fixed end of the imaging section.

50. The device according to claim 46, wherein at least some of the tension members are generally parallel to the longitudinal axis.

51. The system according to claim 46, wherein the portion of the patient in the field of view is the patient'"'"'s torso, the longitudinal axis being generally vertical, such that the patient'"'"'s torso extends generally vertically with the patient'"'"'s head substantially higher than the patient'"'"'s hips.

52. The system according to claim 51, wherein the base comprises a chair-like structure having a generally horizontal bottom portion for supporting the patient'"'"'s hips and a generally vertical back portion of supporting the patient'"'"'s back.

53. A medical imaging device comprising:

a support base;

an imaging section for imaging a field of view, the imaging section extending between a fixed end supported by the base and a free end spaced therefrom, the imaging section including a support assembly comprising;

a first support member having a fixed end supported by the base and a free end spaced therefrom;

a second support member spaced from the first support member by a distance and having a fixed end supported by the base and a free end spaced therefrom; and

a plurality of tension members extending between the first and second support members, the tension members being spaced apart between the fixed and free ends of the support members, each tension member having a first end interconnected with the first support member and a second end interconnected with the second support member, the tension members being adjustable such that the distance between the first and second ends is adjusted.